SCHEMBL6410180

SCHEMBL6410180

COc1ccc(COCC2C(C(=O)O)C2(C)C)c(OC)c1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.42
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
HSD17B10 Q99714 1/20 0.41
ALDH1A1 P00352 3/20 0.41
TAS1R3 Q7RTX0 1/20 0.41
TAS1R1 Q7RTX1 1/20 0.41
TSHR P16473 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
APLNR P35414 1/20 0.40
S1PR1 P21453 1/20 0.40
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6412497 0.89 KMT2A (0.43) CA2MEN1KMT2AALDH1A1TAS1R3
SCHEMBL6474364 0.86 ALDH1A1 (0.49) CA2MEN1KMT2AALDH1A1TSHR
SCHEMBL6409443 0.85 S1PR1 (0.41) CA2MEN1KMT2AALDH1A1TAS1R3
SCHEMBL6406805 0.82 KMT2A (0.47) CA2MEN1KMT2AALDH1A1TSHR
SCHEMBL6406010 0.81 MMP1 (0.45) CA2ALDH1A1POLBMAPTTDP1
SCHEMBL6412672 0.79 S1PR1 (0.37) CA2MEN1KMT2AALDH1A1TSHR
SCHEMBL27606320 0.77 MEN1 (0.42) CA2MEN1KMT2AHSD17B10ALDH1A1
SCHEMBL27606274 0.77 FFAR4 (0.49) CA2MEN1KMT2AHSD17B10ALDH1A1
SCHEMBL6410411 0.76 MAPT (0.44) MEN1KMT2AALDH1A1TSHRNPSR1
SCHEMBL6408337 0.75 FFAR1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids SUMITOMO CHEMICAL COMPAY LIMTED (JP) 2005-12-29 US disclosed
CN-1681767-A Method for manufacturing 2-(hydroxymethyl) cyclopropane carboxylic acid compound SUMITOMO CHEMICAL CO (JP) 2005-10-12 CN disclosed
EP-1538141-A1 PROCESS FOR PRODUCTION OF 2-(HYDROXYMETHYL)CYCLO- PROPANECARBOXYLIC ACIDS Sumitomo Chemical Company, Limited (JP) 2005-06-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids GRHPR, PCCA, C5 CA2 379/4885MEN1 333/4885KMT2A 586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.