Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.56 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6410978 | 0.87 | FKBP1A (0.48) | FKBP1AENPP2MAPTMEN1KMT2A | |
| SCHEMBL6411459 | 0.86 | FKBP1A (0.58) | FKBP1AENPP2MAPTMEN1KMT2A | |
| SCHEMBL6413986 | 0.83 | FKBP1A (0.46) | FKBP1AENPP2MAPTMEN1KMT2A | |
| SCHEMBL6416570 | 0.82 | PKM (0.47) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL2402439 | 0.79 | ALDH1A1 (0.52) | FKBP1AENPP2MAPTMEN1KMT2A | |
| SCHEMBL2399331 | 0.79 | FKBP1A (0.61) | FKBP1AENPP2MAPTMEN1KMT2A | |
| SCHEMBL6419550 | 0.78 | RAB9A (0.54) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL2399304 | 0.76 | FKBP1A (0.48) | FKBP1AENPP2MAPTMEN1KMT2A | |
| SCHEMBL6411430 | 0.73 | RAB9A (0.47) | MEN1KMT2APOLBALDH1A1GAA | |
| SCHEMBL15837602 | 0.73 | MEN1 (0.56) | MEN1KMT2APOLBALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401841-B1 | SUBSTITUTED 1-OXA-2,8-DIAZA-SPIRO 4,5]DEC-2-ENE DERIVATIVES AS MEDICAMENTS FOR THE TREATMENT OF PAIN | GRUENENTHAL GMBH (DE) | 2005-08-24 | — | — | EP | disclosed |