Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6410962 | 0.87 | PKM (0.50) | MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL6410874 | 0.86 | PKM (0.46) | MEN1KMT2AALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL6410522 | 0.86 | MEN1 (0.53) | MEN1KMT2AEPHX2LIPEPRCP | |
| SCHEMBL6417720 | 0.85 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL6409449 | 0.84 | CYP2C19 (0.49) | MEN1KMT2AALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL6410302 | 0.84 | SMN1; SMN2 (0.58) | MEN1KMT2AALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL6410885 | 0.84 | EPHX2 (0.58) | MEN1KMT2AEPHX2LIPEPRCP | |
| SCHEMBL6410851 | 0.82 | HSD11B1 (0.47) | EPHX2SCN9A | |
| SCHEMBL6409740 | 0.82 | LIPE (0.45) | MEN1KMT2AEPHX2LIPEPRCP | |
| SCHEMBL6410676 | 0.82 | MEN1 (0.41) | MEN1KMT2AEPHX2LIPEPRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401841-B1 | SUBSTITUTED 1-OXA-2,8-DIAZA-SPIRO 4,5]DEC-2-ENE DERIVATIVES AS MEDICAMENTS FOR THE TREATMENT OF PAIN | GRUENENTHAL GMBH (DE) | 2005-08-24 | — | — | EP | disclosed |