Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MLYCD | O95822 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.48 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31017510 | 0.86 | GPR119 (0.56) | GPR119NAMPTSMN1; SMN2MAPTLMNA | |
| SCHEMBL13033394 | 0.86 | GPR119 (0.56) | GPR119NAMPTSMN1; SMN2MAPTLMNA | |
| SCHEMBL30083267 | 0.86 | ALDH1A1 (0.58) | GPR119NAMPTMAPTLMNAMEN1 | |
| SCHEMBL6495092 | 0.86 | PARP14 (0.59) | GPR119NAMPTSMN1; SMN2MAPTLMNA | |
| SCHEMBL62718 | 0.86 | ALDH1A1 (0.58) | GPR119NAMPTMAPTLMNAMEN1 | |
| SCHEMBL2333786 | 0.86 | GPR119 (0.58) | GPR119NAMPTSMN1; SMN2MAPTLMNA | |
| SCHEMBL8492447 | 0.85 | SMN1; SMN2 (0.53) | GPR119NAMPTSMN1; SMN2MAPTLMNA | |
| SCHEMBL13702429 | 0.84 | MAPT (0.57) | SMN1; SMN2MAPTLMNAMEN1KMT2A | |
| SCHEMBL13216195 | 0.83 | NAMPT (0.61) | GPR119NAMPTSMN1; SMN2MAPTLMNA | |
| SCHEMBL23228892 | 0.83 | GPR119 (0.55) | GPR119NAMPTSMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050130989-A1 | N-arylheteroaromatic products compositions containing them and use thereof | AVENTIS PHARMA S. A. (FR) | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050130989-A1 | N-arylheteroaromatic products compositions containing them and use thereof | AHR, NQO1, ARNT | GPR119 2889/4885NAMPT 170/4885SMN1; SMN2 3810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.