Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25748781 | 0.85 | TGFBR1 (0.42) | TGFBR1TSHRALDH1A1THRBRXFP1 | |
| SCHEMBL9322447 | 0.82 | TSHR (0.47) | TGFBR1TSHRALDH1A1RXFP1 | |
| SCHEMBL9321557 | 0.82 | TSHR (0.40) | TGFBR1TSHRALDH1A1HSD17B10 | |
| SCHEMBL7695367 | 0.82 | TGFBR1 (0.46) | TGFBR1TSHRALDH1A1MGAMGAA | |
| SCHEMBL8615608 | 0.81 | TGFBR1 (0.46) | TGFBR1TSHRALDH1A1RXFP1 | |
| SCHEMBL9135825 | 0.81 | TGFBR1 (0.42) | TGFBR1TSHRALDH1A1MGAMGAA | |
| SCHEMBL9577882 | 0.80 | TGFBR1 (0.44) | TGFBR1TSHRALDH1A1MGAMGAA | |
| SCHEMBL10766136 | 0.80 | TGFBR1 (0.44) | TGFBR1TSHRALDH1A1MGAMGAA | |
| SCHEMBL7523056 | 0.79 | — | — | |
| SCHEMBL4958110 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 407 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12611016-B2 | Cationic contact lens | COOPERVISION INTERNATIONAL LIMITED (GB) | 2026-04-28 | — | — | US | claimed |
| US-12601929-B2 | Contact lens | COOPERVISION INTERNATIONAL LIMITED (GB) | 2026-04-14 | — | — | US | claimed |
| EP-4413404-B1 | CATIONIC CONTACT LENS | COOPERVISION INT LTD (GB) | 2025-10-15 | — | — | EP | claimed |
| EP-4537135-B1 | CONTACT LENS AND PACKAGING SOLUTION | COOPERVISION INT LTD (GB) | 2025-09-17 | — | — | EP | claimed |
| EP-4413405-B1 | SUSTAINED RELEASE OF OLEIC ACID FROM CONTACT LENSES | COOPERVISION INT LTD (GB) | 2025-06-18 | — | — | EP | claimed |
| WO-2025088339-A1 | CONTACT LENS WITH TRPM8 AGONIST IS RELEASABLY ADHERED TO THE POLYMERIC LENS BODY | COOPERVISION INTERNATIONAL LIMITED (GB) | 2025-05-01 | — | — | WO | claimed |
| US-12282209-B1 | Contact lens and packaging solution | COOPERVISION INTERNATIONAL LIMITED (GB) | 2025-04-22 | — | — | US | claimed |
| EP-4537135-A1 | CONTACT LENS AND PACKAGING SOLUTION | CooperVision International Limited (GB) | 2025-04-16 | — | — | EP | claimed |
| EP-4388349-B1 | CONTACT LENS | COOPERVISION INT LTD (GB) | 2025-03-12 | — | — | EP | claimed |
| CN-116391140-B | Cationic contact lens | 库博光学国际有限公司 | 2025-01-10 | — | — | CN | claimed |
| EP-2681614-B1 | WETTABLE SILICONE HYDROGEL CONTACT LENSES | COOPERVISION INT LTD (GB) | 2021-05-05 | — | — | EP | claimed |
| US-9164298-B2 | Wettable silicone hydrogel contact lenses | COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) | 2015-10-20 | — | — | US | claimed |
| US-20140335610-A1 | CELL CULTURE SUBSTRATE, AND METHOD FOR MANUFACTURING SAME | TOKYO WOMEN'S MEDICAL UNIVERSITY (JP) | 2014-11-13 | — | — | US | claimed |
| US-8865789-B2 | Silicone hydrogel contact lenses | COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) | 2014-10-21 | — | — | US | claimed |
| US-20140022506-A1 | Wettable Silicone Hydrogel Contact Lenses | COOPER VISION INTERNATIONAL HOLDING COMPANY ,LP (BB) | 2014-01-23 | — | — | US | claimed |
| WO-2012118678-A1 | WETTABLE SILICONE HYDROGEL CONTACT LENSES | COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) | 2012-09-07 | — | — | WO | claimed |
| WO-2012118674-A2 | SILICONE HYDROGEL CONTACT LENSES | COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) | 2012-09-07 | — | — | WO | claimed |
| US-20120220689-A1 | Silicone Hydrogel Contact Lenses | COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) | 2012-08-30 | — | — | US | claimed |
| EP-2492718-A1 | Silicone Hydrogel Contact Lenses | CooperVision International Holding Company, LP (BB) | 2012-08-29 | — | — | EP | claimed |
| EP-1829896-B1 | PROCESS FOR PRODUCTION OF ORGANIC-INORGANIC HYBRID HYDROGEL, CELL CULTURE SUBSTRATE COMPRISING THE SAME, AND ANTIFOGGING MATERIAL COMPRISING DRIED PRODUCT THEREOF | KAWAMURA INST CHEM RES (JP) | 2010-06-16 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12601929-B2 | Contact lens | TRPM8, TRPM7, TRPM5 | TGFBR1 3405/4885TSHR 4239/4885ALDH1A1 4075/4885 |
| US-12611016-B2 | Cationic contact lens | SMCHD1, SSB, SMC2 | TGFBR1 328/4885TSHR 1242/4885ALDH1A1 3249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.