Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | CYP26A1 | O43174 | 6/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29351105 | 1.00 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2TP53CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL22589709 | 0.99 | ALDH1A1 (0.98) | ALDH1A1SMN1; SMN2TP53CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL29393982 | 0.99 | ALDH1A1 (0.98) | ALDH1A1SMN1; SMN2TP53CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL7706186 | 0.89 | ALDH1A1 (0.80) | ALDH1A1SMN1; SMN2TP53CYP1A2CYP3A4 | |
| SCHEMBL29393503 | 0.84 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2TP53CYP1A2CYP3A4 | |
| SCHEMBL8583021 | 0.84 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2TP53CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL9136732 | 0.83 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2TP53CYP1A2CYP3A4 | |
| SCHEMBL29367407 | 0.83 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2TP53CYP1A2CYP3A4 | |
| SCHEMBL29391674 | 0.82 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2TP53CYP1A2CYP3A4 | |
| SCHEMBL9445110 | 0.82 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2TP53CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858649-B1 | TREATMENT OF MOTOR AND MOVEMENT DISORDER SIDE EFFECTS ASSOCIATED WITH PARKINSON'S DISEASE TREATMENTS | PSYCHOGENICS INC (US) | 2019-10-23 | — | — | EP | claimed |
| US-9034798-B2 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | CAPROTEC BIOANALYTICS GMBH (DE) | 2015-05-19 | — | — | US | disclosed |
| EP-2858649-A2 | TREATMENT OF MOTOR AND MOVEMENT DISORDER SIDE EFFECTS ASSOCIATED WITH PARKINSON'S DISEASE TREATMENTS | Psychogenics Inc. (US) | 2015-04-15 | — | — | EP | disclosed |
| WO-2013188210-A2 | TREATMENT OF MOTOR AND MOVEMENT DISORDER SIDE EFFECTS ASSOCIATED WITH PARKINSON'S DISEASE TREATMENTS | PSYCHOGENICS, INC. (US) | 2013-12-19 | — | — | WO | disclosed |
| US-8569481-B2 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | PHARMACEUTICALS, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-20110118136-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | KOESTER HUBERT | 2011-05-19 | — | — | US | disclosed |
| US-7858560-B2 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | CAPROTEC BIOANALYTICS GMBH (DE) | 2010-12-28 | — | — | US | disclosed |
| US-20100298168-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | HK PHARMACEUTICALS, INC. | 2010-11-25 | — | — | US | disclosed |
| US-20100248264-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | HK PHARMACEUTICALS, INC. | 2010-09-30 | — | — | US | disclosed |
| EP-1485707-B1 | CAPTURE COMPOUNDS, COLLECTIONS THEREOF AND METHODS FOR ANALYZING THE PROTEOME AND COMPLEX COMPOSITIONS | CAPROTEC BIOANALYTICS GMBH (DE) | 2009-01-14 | — | — | EP | disclosed |
| US-20050187222-A1 | Nitrosated and nitrosylated alpha-adrenergic receptor antagonist compounds | NITROMED, INC. (US) | 2005-08-25 | — | — | US | disclosed |
| US-20020143007-A1 | Nitrosated and nitrosylated alpha-adrenergic receptor antagonists, compositions and methods of use | GARVEY DAVID S (US) | 2002-10-03 | — | — | US | disclosed |
| US-6162455-A | Method for increasing lean meat, improving the lean meat to fat ratio and improving amino acid utilization in warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 2000-12-19 | — | — | US | disclosed |
| US-5994294-A | Nitrosated and nitrosylated α-adrenergic receptor antagonist compounds, compositions and their uses | NITROMED, INC. (US) | 1999-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187222-A1 | Nitrosated and nitrosylated alpha-adrenergic receptor antagonist compounds | ADRB1, ADRB3, ADRA1D | ALDH1A1 628/4885SMN1; SMN2 1602/4885TP53 2341/4885 |
| US-20110118136-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | PTMS, QPCTL, SRMS | ALDH1A1 4360/4885SMN1; SMN2 4623/4885TP53 1648/4885 |
| US-20020143007-A1 | Nitrosated and nitrosylated alpha-adrenergic receptor antagonists, compositions and methods of use | ADRB1, ADRB3, ADRA1D | ALDH1A1 610/4885SMN1; SMN2 1516/4885TP53 2595/4885 |
| US-20100298168-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | CHLSN, PTMS, SRMS | ALDH1A1 4064/4885SMN1; SMN2 3130/4885TP53 1173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.