Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6410292 | 0.81 | HSPA5 (0.62) | HSPA5ALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11389610 | 0.80 | GPR35 (0.67) | GPR35AKR1B1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL6409044 | 0.79 | KMT2A (0.50) | GPR35HSPA5ALDH1A1KMT2AGAA | |
| SCHEMBL28799087 | 0.78 | ALDH1A1 (0.63) | GPR35ALDH1A1KMT2AGAAPTPN1 | |
| SCHEMBL4346301 | 0.76 | MEN1 (0.46) | ABCB1HSPA5ALDH1A1KMT2AGAA | |
| SCHEMBL6408389 | 0.76 | TP53 (0.43) | HSPA5ALDH1A1KMT2AGAAMAPT | |
| SCHEMBL9313912 | 0.76 | GPR35 (0.54) | GPR35AKR1B1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL6408384 | 0.75 | HSPA5 (0.52) | GPR35HSPA5ALDH1A1KMT2AGAA | |
| SCHEMBL9400489 | 0.74 | HSPA5 (0.58) | HSPA5ALDH1A1KMT2AMAPTNPC1 | |
| SCHEMBL11728688 | 0.74 | NPC1 (0.59) | GPR35ABCB1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050124667-A1 | Oxamide inhibitors of plasminogen activator inhibitor-1 | CEREP SA (FR) | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124667-A1 | Oxamide inhibitors of plasminogen activator inhibitor-1 | SERPINE1, SERPINC1, SERPINB1 | GPR35 3140/4885AKR1B1 156/4885ABCB1 1098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.