Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 14/20 | 0.46 |
| ▸ | NQO2 | P16083 | 13/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 13/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6414529 | 1.00 | MTNR1A (0.46) | MTNR1ANQO2MTNR1BBRD4KMT2A | |
| SCHEMBL7078710 | 0.84 | PDE3B (0.42) | BRD4KMT2A | |
| SCHEMBL6197387 | 0.82 | ALOX15 (0.42) | MTNR1ANQO2MTNR1BKMT2A | |
| SCHEMBL6197384 | 0.82 | ALOX15 (0.42) | MTNR1ANQO2MTNR1BKMT2A | |
| SCHEMBL6197391 | 0.82 | ALOX15 (0.42) | MTNR1ANQO2MTNR1BKMT2A | |
| SCHEMBL14061903 | 0.79 | CYP24A1 (0.57) | — | |
| SCHEMBL6414524 | 0.77 | DPP4 (0.43) | MTNR1ANQO2MTNR1BKMT2A | |
| SCHEMBL7076204 | 0.77 | BRD4 (0.39) | BRD4KMT2A | |
| SCHEMBL4623734 | 0.76 | SIRT1 (0.46) | MTNR1AMTNR1B | |
| SCHEMBL17049209 | 0.75 | ALDH1A1 (0.48) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050234041-A1 | Substituted 1-benzazepines and derivatives thereof | BIOPORT R&D, INC. | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234041-A1 | Substituted 1-benzazepines and derivatives thereof | BAK1, BAD, BAX | MTNR1A 2087/4885NQO2 1761/4885MTNR1B 1546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.