Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 4/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.37 |
| ▸ | APAF1 | O14727 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5827488 | 0.72 | ALPI (0.47) | APAF1 | |
| SCHEMBL9702510 | 0.70 | ESR1 (0.50) | CYP2C19LMNAHSD17B10ESR1ESR2 | |
| SCHEMBL5156210 | 0.70 | ESR1 (0.61) | LMNAHSD17B10ESR1ESR2POLB | |
| SCHEMBL7087165 | 0.69 | ESR1 (0.48) | CYP2C19LMNAHSD17B10ESR1ESR2 | |
| SCHEMBL5488862 | 0.68 | ESR1 (0.47) | CYP2C19LMNAHSD17B10ESR1ESR2 | |
| SCHEMBL11248515 | 0.68 | PTGS1 (0.61) | CYP2C19LMNAHSD17B10ESR1ESR2 | |
| SCHEMBL819392 | 0.68 | LMNA (0.61) | CYP2C19LMNAHSD17B10ESR1ESR2 | |
| SCHEMBL4795362 | 0.68 | ESR1 (0.47) | CYP2C19LMNAHSD17B10ESR1ESR2 | |
| SCHEMBL1118743 | 0.68 | TAAR1 (0.52) | CYP2C19LMNAHSD17B10ESR1ESR2 | |
| SCHEMBL1118667 | 0.68 | TAAR1 (0.52) | CYP2C19LMNAHSD17B10ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6861458-B2 | Photoprotective and lightfastness-enhancing siloxanes | XEROX CORPORATION (US) | 2005-03-01 | — | — | US | disclosed |