SCHEMBL819392

SCHEMBL819392

CCC(C(=O)O)c1ccc(O)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.61
HSD17B10 Q99714 2/20 0.61
ESR1 P03372 6/20 0.54
PTGS1 P23219 3/20 0.54
ADRA1A P35348 2/20 0.54
CYP2C9 P11712 2/20 0.54
CYP1A2 P05177 1/20 0.54
PGR P06401 1/20 0.54
CHRM2 P08172 1/20 0.54
CYP3A4 P08684 1/20 0.54
ADORA3 P0DMS8 1/20 0.54
AR P10275 1/20 0.54
CYP2D6 P10635 1/20 0.54
MAPT P10636 1/20 0.54
CHRM1 P11229 1/20 0.54
ALOX15 P16050 1/20 0.54
DRD1 P21728 1/20 0.54
TBXA2R P21731 1/20 0.54
SLC6A2 P23975 1/20 0.54
CYP2C19 P33261 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1574429 0.91 AKR1C3 (0.58) LMNAHSD17B10PTGS1ADRA1ACYP2C9
SCHEMBL2523917 0.91 LMNA (0.53) LMNAHSD17B10ESR1PTGS1ADRA1A
SCHEMBL633268 0.84 ESR1 (0.49) LMNAHSD17B10ESR1PTGS1ADRA1A
SCHEMBL510548 0.83 ALDH1A1 (0.56) LMNAHSD17B10PTGS1ADRA1AAKR1C3
SCHEMBL7705115 0.83 ALDH1A1 (0.56) LMNAHSD17B10PTGS1ADRA1AAKR1C3
SCHEMBL1715 0.83 LMNA (0.59) LMNAHSD17B10ADRA1ACYP2D6MAPT
SCHEMBL65737 0.83 LMNA (0.59) LMNAHSD17B10ADRA1ACYP2D6MAPT
SCHEMBL20769804 0.83 LMNA (0.59) LMNAHSD17B10ADRA1ACYP2D6MAPT
SCHEMBL67237 0.83 LMNA (0.59) LMNAHSD17B10ADRA1ACYP2D6MAPT
SCHEMBL9702510 0.83 ESR1 (0.50) LMNAHSD17B10ESR1PTGS1ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120053390-A Alfacalcidol soft capsule and preparation method thereof 江苏东科康德药业有限公司 2025-05-30 CN claimed
CN-115252572-B Alfacalcidol soft capsule and preparation method thereof 南通华山药业有限公司 2024-03-29 CN claimed
CN-117487318-B Fireproof bus duct based on epoxy resin and preparation method thereof 江苏盈聚电气有限公司 2024-03-22 CN claimed
CN-117487318-A Fireproof bus duct based on epoxy resin and preparation method thereof 江苏盈聚电气有限公司 2024-02-02 CN claimed
CN-103215091-B Biodiesel composition and method for increasing oxidation stability of biodiesel-containing fuel CHINA PETROLEUM & CHEMICAL 2015-02-25 CN claimed
CN-102627670-B Aryl alkyl acid-cyclophosphamide derivative as well as preparation method and application thereof UNIV SHIJIAZHUANG 2014-11-26 CN claimed
CN-103215091-A Biodiesel composition and method for increasing oxidation stability of biodiesel-containing fuel CHINA PETROLEUM & CHEMICAL 2013-07-24 CN claimed
US-8048896-B2 Inhibit nonenzymatic formation of advanced glycation end-products (AGE) using e.g. aminoguanidine, OPB-9195 [(+/-)-2-isopropylidenehydrazono-4-oxo-thiazolidin-5-yla cetanilide], pyridoxamine, antioxidants, alagebrium, antihypertensives, angiotensin-converting enzyme inhibitors Cell Viable Corporation (US) 2011-11-01 US claimed
CN-101613630-A Biodiesel composition and method for improving oxidation stability of biodiesel-containing fuel CHINA PETROLEUM & CHEMICAL 2009-12-30 CN claimed
EP-1165064-B1 NOVEL INHIBITORS OF FORMATION OF ADVANCED GLYCATION ENDPRODUCTS (AGE'S) HOPE CITY (US) 2004-02-25 EP claimed
US-6337350-B1 CROSSLINKING INHIBITION OF PROTEINS CITY OF HOPE 2002-01-08 US claimed
EP-1165064-A2 NOVEL INHIBITORS OF FORMATION OF ADVANCED GLYCATION ENDPRODUCTS (AGE'S) City of Hope (US) 2002-01-02 EP claimed
WO-2000059875-A2 NOVEL INHIBITORS OF FORMATION OF ADVANCED GLYCATION ENDPRODUCTS (AGE'S) CITY OF HOPE (US) 2000-10-12 WO claimed
US-5233012-A Phenolic resins flow control agents; storage stability, workability, heat resistance SANYO-KOKUSAKU PULP CO., LTD. (JP) 1993-08-03 US claimed
EP-0083335-A1 Optically active chiral compounds, process for their preparation and use of these compounds in the protection of functional -OH, -SH, -NH- groups, in the separation of racemates, in the preparation of optically active imidoester hydrochlorides and of optically active esters, in the preparation of optically enriched alcohols and in the preparation of optically active compounds by asymmetric induction Noe, Christian, Dipl.-Ing. Dr. (AT) 1983-07-06 EP claimed
CN-120053390-A Alfacalcidol soft capsule and preparation method thereof 江苏东科康德药业有限公司 2025-05-30 CN disclosed
CN-118754842-A Tryptophan derivative and preparation method and application thereof 中国人民解放军北部战区总医院 2024-10-11 CN disclosed
US-4153599-A Monoazo-dyes particularly suited to the levelled dyeing of synthetic polyamide fibers AZIENDE COLORI NAZIONALI AFFINI -ACNA S.P.A. (IT) 1979-05-08 US disclosed
US-4077765-A Monoazo-dyes particularly suited to the levelled dyeing of synthetic polyamide fibers AZIENDE COLORI NAZIONALI AFFINI-ACNA S.P.A. (IT) 1978-03-07 US disclosed
US-4057618-A IMAGING AGENT FOR BODY TISSUES UNIVERSITY PATENTS, INC. (US) 1977-11-08 US disclosed