SCHEMBL641554

SCHEMBL641554

CC(C)(C)N(CCS)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
HTT P42858 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
LMNA P02545 2/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19025042 0.88 FOLH1 (0.36) MEN1KMT2AHTTL3MBTL1
SCHEMBL10384650 0.81 MEN1 (0.34) MEN1KMT2AHTTL3MBTL1LMNA
SCHEMBL332512 0.78 CA12 (0.36) MEN1KMT2AHTTL3MBTL1LMNA
SCHEMBL319857 0.78 MEN1 (0.35) MEN1KMT2AHTTL3MBTL1LMNA
SCHEMBL246225 0.76 MEN1 (0.34) MEN1KMT2AHTTL3MBTL1LMNA
SCHEMBL3898144 0.76 HTT (0.34) MEN1KMT2AHTTL3MBTL1LMNA
SCHEMBL3397667 0.76 MEN1 (0.34) MEN1KMT2AHTTL3MBTL1LMNA
SCHEMBL24101 0.76 MEN1 (0.34) MEN1KMT2AHTTL3MBTL1LMNA
Bicarbonate SCHEMBL4130664 0.74 MEN1 (0.33) MEN1KMT2AHTTL3MBTL1
Hydrochloric Acid SCHEMBL12487855 0.74 KDM4E (0.37) MEN1KMT2AHTTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250066292-A1 CYSTEAMINE AND/OR CYSTAMINE PRODRUGS UNIV CALIFORNIA (US) 2025-02-27 US disclosed
EP-4457211-A2 CYSTEAMINE AND/OR CYSTAMINE PRODRUGS The Regents of the University of California (US) 2024-11-06 EP disclosed
US-20240360149-A1 COMPOUND WITH ANTICANCER ACTIVITY KYOWA KIRIN CO., LTD. (JP) 2024-10-31 US disclosed
EP-4237008-A2 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF Elucida Oncology, Inc. (US) 2023-09-06 EP disclosed
US-20230241243-A1 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF ELUCIDA ONCOLOGY, INC. 2023-08-03 US disclosed
WO-2023129584-A2 CYSTEAMINE AND/OR CYSTAMINE PRODRUGS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-07-06 WO disclosed
WO-2022093800-A2 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF ELUCIDA ONCOLOGY, INC. (US) 2022-05-05 WO disclosed
CN-106458957-B Novel cell permeable succinic acid compounds 爱博利瓦有限公司 2020-08-18 CN disclosed
US-10369138-B2 Monobactam organic compounds for the treatment of bacterial infections NOVARTIS AG (CH) 2019-08-06 US disclosed
US-9409952-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2016-08-09 US disclosed
US-6504034-B2 Cell antiproliferative agents; anticancer agents HOFFMANN-LA ROCHE INC. 2003-01-07 US disclosed
US-20020147343-A1 Naphthostyrils CHEN YI (US) 2002-10-10 US disclosed
EP-1036059-B1 ADAMANTANE DERIVATIVES ASTRAZENECA UK LTD (GB) 2002-09-18 EP disclosed
WO-2002059109-A2 NAPHTHOSTYRIL DERIVATIVES AND THEIR USE AS INHIBITORS OF CYCLIN- DEPENDENT KINASES F. HOFFMANN-LA ROCHE AG (CH) 2002-08-01 WO disclosed
US-6303659-B2 Compounds ASTRAZENECA AB (SE) 2001-10-16 US disclosed
US-6258838-B1 Compounds ASTRAZENECA AB (SE) 2001-07-10 US disclosed
US-20010003121-A1 Novel compounds ASTRAZENECA UK LIMITED 2001-06-07 US disclosed
US-6201024-B1 EFFECTIVE P2X7 RECEPTOR ANTAGONISTS FOR USE IN THE TREATMENT OF INFLAMMATORY, IMMUNE OR CARDIOVASCULAR DISORDERS ASTRAZENECA UK LIMITED (GB) 2001-03-13 US disclosed
EP-1036059-A1 ADAMANTANE DERIVATIVES AstraZeneca UK Limited (GB) 2000-09-20 EP disclosed
WO-1999029661-A1 ADAMANTANE DERIVATIVES ASTRAZENECA UK LIMITED (GB) 1999-06-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250066292-A1 CYSTEAMINE AND/OR CYSTAMINE PRODRUGS SLC7A11, FABP1, CBS MEN1 3097/4885KMT2A 3663/4885HTT 474/4885
US-20020147343-A1 Naphthostyrils CCNI, CDKL1, CDK2 MEN1 2355/4885KMT2A 2197/4885HTT 4212/4885
US-20230241243-A1 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF NDC1, KIFC1, SDCBP MEN1 2314/4885KMT2A 4146/4885HTT 1399/4885
US-10369138-B2 Monobactam organic compounds for the treatment of bacterial infections MGAM, MGAM2, BPGM MEN1 1714/4885KMT2A 2273/4885HTT 4722/4885
US-20010003121-A1 Novel compounds APP, BACE1, CHRNA5 MEN1 1930/4885KMT2A 4437/4885HTT 1284/4885
US-20240360149-A1 COMPOUND WITH ANTICANCER ACTIVITY TP53, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, RCC2 MEN1 41/4885KMT2A 2349/4885HTT 2265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.