SCHEMBL6416075

SCHEMBL6416075

CC[Sn](CC)(CC)c1ncco1.[Li]CCCC

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.32
CES1 P23141 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3353972 0.86
SCHEMBL426377 0.79 FAAH (0.35) FAAHCES1
SCHEMBL13735602 0.74 FAAH (0.30) FAAHCES1
Hydrochloric Acid SCHEMBL4697536 0.74 FAAH (0.34) FAAHCES1
Hydrochloric Acid SCHEMBL4697538 0.72 FAAH (0.36) FAAHCES1
SCHEMBL6418155 0.65 ATM (0.41) FAAHCES1
SCHEMBL8499928 0.63
SCHEMBL28365975 0.62 FAAH (0.36) FAAHCES1
SCHEMBL4595010 0.61
Hydrochloric Acid SCHEMBL6916105 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1499616-A1 HETEROCYCLIC COMPOUNDS AstraZeneca AB (SE) 2005-01-26 EP disclosed
WO-2003087104-A1 HETEROCYCLIC COMPOUNDS ASTRAZENECA AB (SE) 2003-10-23 WO disclosed