Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.57 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.57 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.57 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6339286 | 0.84 | ABCC9 (0.60) | ABCC9ABCC8KCNJ11KCNJ8EPHX2 | |
| SCHEMBL5110259 | 0.82 | ABCC9 (0.57) | ABCC9ABCC8KCNJ11KCNJ8EPHX2 | |
| SCHEMBL5113168 | 0.77 | ABCC9 (0.48) | ABCC9ABCC8KCNJ11KCNJ8EPHX2 | |
| SCHEMBL5116247 | 0.76 | ABCC9 (0.60) | ABCC9ABCC8KCNJ11KCNJ8EPHX2 | |
| SCHEMBL5111868 | 0.74 | MAOA (0.81) | ABCC9ABCC8KCNJ11KCNJ8EPHX2 | |
| SCHEMBL5113896 | 0.73 | ABCC9 (1.00) | ABCC9ABCC8KCNJ11KCNJ8EPHX2 | |
| SCHEMBL5113480 | 0.70 | ABCC9 (0.51) | ABCC9ABCC8KCNJ11KCNJ8EPHX2 | |
| SCHEMBL5110631 | 0.68 | LMNA (0.55) | ABCC9ABCC8KCNJ11KCNJ8EPHX2 | |
| SCHEMBL5110628 | 0.68 | ABCC9 (0.51) | ABCC9ABCC8KCNJ11KCNJ8EPHX2 | |
| SCHEMBL5110486 | 0.67 | ABCC9 (0.47) | ABCC9ABCC8KCNJ11KCNJ8EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6967216-B2 | Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by NP Y5 receptor | ASTRAZENECA AB (SE) | 2005-11-22 | — | — | US | disclosed |