SCHEMBL641627

SCHEMBL641627

C=CC(=O)NCC.C=CC(=O)NCCC

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.62
ZDHHC2 Q9UIJ5 1/20 0.62
TSHR P16473 3/20 0.50
ALDH1A1 P00352 3/20 0.50
MAPK1 P28482 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP3 P08254 1/20 0.39
MMP9 P14780 1/20 0.39
EPHX1 P07099 1/20 0.38
GAA P10253 1/20 0.37
LMNA P02545 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MCL1 Q07820 1/20 0.36
TGM2 P21980 3/20 0.35
KDM4C Q9H3R0 1/20 0.34
FAAH O00519 1/20 0.33
THRA P10827 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL141762 0.93
Water SCHEMBL28252943 0.91
Ammonia Solution, Strong SCHEMBL27756085 0.91
SCHEMBL9063855 0.91
Hydrochloric Acid SCHEMBL15846881 0.91
Diethylamine SCHEMBL985871 0.89 ZDHHC20 (0.60) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL2829292 0.89 ZDHHC20 (0.55) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
Hydrochloric Acid SCHEMBL7037481 0.89 ZDHHC20 (0.64) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
Bicarbonate SCHEMBL8365492 0.89 ZDHHC20 (0.64) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL11326540 0.89 ZDHHC20 (0.64) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10463737-B2 Silicone acrylate compositions and methods of preparing the same DOW CORNING CORPORATION (US) 2019-11-05 US disclosed
US-20170368179-A1 SILICONE ACRYLATE COMPOSITIONS AND METHODS OF PREPARING THE SAME DOW CORNING CORPORATION (US) 2017-12-28 US disclosed
EP-3250618-A1 SILICONE ACRYLATE COMPOSITIONS AND METHODS OF PREPARING THE SAME Dow Corning Corporation (US) 2017-12-06 EP disclosed
WO-2016123418-A1 SILICONE ACRYLATE COMPOSITIONS AND METHODS OF PREPARING THE SAME DOW CORNING CORPORATION (US) 2016-08-04 WO disclosed
US-8119743-B2 Silane substituted polyalkylene oxide reagents and methods of using for preventing or reducing aluminosilicate scale in industrial processes CYTEC TECHNOLOGY CORP. (US) 2012-02-21 US disclosed
US-8067507-B2 Compositions for preventing or reducing aluminosilicate scale in industrial processes CYTEC TECHNOLOGY CORP. (US) 2011-11-29 US disclosed
EP-2386578-A2 Method of preventing or reducing aluminosilicate scale in industrial processes Cytec Technology Corp. (US) 2011-11-16 EP disclosed
US-8039658-B2 Removal of trace arsenic impurities from triethylphosphate (TEPO) AIR PRODUCTS AND CHEMICALS, INC. (US) 2011-10-18 US disclosed
US-7988863-B2 Silane substituted polyalkylene oxide reagents and methods of using for preventing or reducin aluminosilicate scale in industrial processes CYTEC TECHNOLOGY CORP. (US) 2011-08-02 US disclosed
US-20100256317-A1 COMPOSITIONS FOR PREVENTING OR REDUCING ALUMINOSILICATE SCALE IN INDUSTRIAL PROCESSES CYTEC TECHNOLOGY CORP. (US) 2010-10-07 US disclosed
US-7674385-B2 Silane substituted polyethylene oxide reagents and method of using for preventing or reducing aluminosilicate scale in industrial processes CYTEC TECHNOLOGY CORP. (US) 2010-03-09 US disclosed
EP-2109590-A1 SILANE SUBSTITUTED POLYETHYLENE OXIDE REAGENTS AND METHOD OF USING FOR PREVENTING OR REDUCING ALUMINOSILICATE SCALE IN INDUSTRIAL PROCESSES CYTEC TECHNOLOGY CORP. (US) 2009-10-21 EP disclosed
WO-2008097671-A1 SILANE SUBSTITUTED POLYETHYLENE OXIDE REAGENTS AND METHOD OF USING FOR PREVENTING OR REDUCING ALUMINOSILICATE SCALE IN INDUSTRIAL PROCESSES CYTEC TECHNOLOGY CORP. (US) 2008-08-14 WO disclosed
US-20080179564-A1 Acrylic polymers with a pendant group or end group containing Si(OR'')3; pulping mill process stream for a Kraft recovery process for manufacturing paper; polymer of a hydroxyethylcellulose derivative reacted with 3-glycidoxypropyltrimethoxysilane and an end group of silane triol; CYTEC TECHNOLOGY CORP. 2008-07-31 US disclosed
US-7390415-B2 Method and compositions for preventing or reducing aluminosilicate scale in alkaline industrial processes CYTEC TECHNOLOGY CORP. (US) 2008-06-24 US disclosed
US-20080111103-A1 SILANE SUBSTITUTED POLYETHYLENE OXIDE REAGENTS AND METHOD OF USING FOR PREVENTING OR REDUCING ALUMINOSILICATE SCALE IN INDUSTRIAL PROCESSES CYTEC TECHNOLOGY CORP. 2008-05-15 US disclosed
EP-1858931-A1 METHOD OF PREVENTING OR REDUCING ALUMINOSILICATE SCALE IN INDUSTRIAL PROCESSES CYTEC TECHNOLOGY CORP. (US) 2007-11-28 EP disclosed
WO-2006086189-A1 METHOD OF PREVENTING OR REDUCING ALUMINOSILICATE SCALE IN INDUSTRIAL PROCESSES CYTEC TECHNOLOGY CORP. (US) 2006-08-17 WO disclosed
US-20060124553-A1 Method of preventing or reducing aluminosilicate scale in high level nuclear wastes CYTEC TECHNOLOGY CORP. 2006-06-15 US disclosed
US-20050274926-A1 Method of preventing or reducing aluminosilicate scale in kraft pulp mills CYTEC TECHNOLOGY CORP. 2005-12-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10463737-B2 Silicone acrylate compositions and methods of preparing the same ACR, CAD, MMAB ZDHHC20 3788/4885ZDHHC2 4280/4885TSHR 2886/4885
US-20170368179-A1 SILICONE ACRYLATE COMPOSITIONS AND METHODS OF PREPARING THE SAME ACR, CAD, MMAB ZDHHC20 3788/4885ZDHHC2 4280/4885TSHR 2886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.