Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNF4 | P78317 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | MITF | O75030 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3382618 | 0.89 | RNF4 (1.00) | RNF4ALDH1A1POLBHTTMITF | |
| SCHEMBL2000889 | 0.87 | RNF4 (0.77) | RNF4ALDH1A1POLBHTTMEN1 | |
| SCHEMBL5364516 | 0.85 | HTT (0.59) | RNF4ALDH1A1POLBHTTMITF | |
| SCHEMBL10617946 | 0.83 | NPC1 (0.57) | RNF4ALDH1A1POLBHTTMITF | |
| SCHEMBL20942365 | 0.83 | RNF4 (0.71) | RNF4ALDH1A1POLBHTTMEN1 | |
| SCHEMBL11806908 | 0.81 | RNF4 (0.86) | RNF4ALDH1A1POLBHTTMITF | |
| SCHEMBL6411466 | 0.81 | L3MBTL1 (0.63) | ALDH1A1HTTMAPK1MEN1KMT2A | |
| SCHEMBL23323205 | 0.79 | POLB (0.68) | RNF4ALDH1A1POLBHTTMEN1 | |
| SCHEMBL20941574 | 0.79 | MEN1 (0.68) | RNF4ALDH1A1POLBHTTMEN1 | |
| SCHEMBL20942366 | 0.79 | RNF4 (0.67) | RNF4ALDH1A1POLBHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998989-B2 | 2-Imino-1,3-thiazoline-based compounds and T-type calcium channel inhibitors containing the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2011-08-16 | — | — | US | disclosed |
| US-7998989-B2 | 2-Imino-1,3-thiazoline-based compounds and T-type calcium channel inhibitors containing the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2011-08-16 | — | — | US | disclosed |
| US-20080293786-A1 | NOVEL 2-IMINO-1,3-THIAZOLINE-BASED COMPOUNDS AND T-TYPE CALCIUM CHANNEL INHIBITORS CONTAINING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2008-11-27 | — | — | US | disclosed |
| US-20080293786-A1 | NOVEL 2-IMINO-1,3-THIAZOLINE-BASED COMPOUNDS AND T-TYPE CALCIUM CHANNEL INHIBITORS CONTAINING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2008-11-27 | — | — | US | disclosed |
| US-6921770-B2 | 2-Phenyliminothiazolines, their preparation method and anti-rice blast agent containing the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2005-07-26 | — | — | US | disclosed |
| EP-1311160-A4 | 2-PHENYLIMINOTHIAZOLINES, THEIR PREPARATION METHOD AND ANTI-RICE BLAST AGENT CONTAINING THE SAME | KOREA INST SCI & TECH (KR) | 2004-04-21 | — | — | EP | disclosed |
| US-20030203950-A1 | 2-Phenyliminothiazolines, their preparation method and anti-rice blast agent containing the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2003-10-30 | — | — | US | disclosed |
| EP-1311160-A1 | 2-PHENYLIMINOTHIAZOLINES, THEIR PREPARATION METHOD AND ANTI-RICE BLAST AGENT CONTAINING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002013611-A1 | 2-PHENYLIMINOTHIAZOLINES, THEIR PREPARATION METHOD AND ANTI-RICE BLAST AGENT CONTAINING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2002-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203950-A1 | 2-Phenyliminothiazolines, their preparation method and anti-rice blast agent containing the same | TYR, SYPL1, SSBP1 | RNF4 4775/4885ALDH1A1 4656/4885POLB 2313/4885 |
| US-20080293786-A1 | NOVEL 2-IMINO-1,3-THIAZOLINE-BASED COMPOUNDS AND T-TYPE CALCIUM CHANNEL INHIBITORS CONTAINING THE SAME | CACNA1I, CACNA1H, CACNA1G | RNF4 4517/4885ALDH1A1 2247/4885POLB 4790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.