Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | MC5R | P33032 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2400578 | 0.86 | NPC1 (0.46) | KMT2AMEN1FAAHNPC1PKM | |
| SCHEMBL2400871 | 0.86 | MEN1 (0.44) | KMT2AMEN1MC4RMC5RFAAH | |
| SCHEMBL2405120 | 0.82 | GAA (0.47) | KMT2AMEN1 | |
| Dimethylamine SCHEMBL2580728 | 0.73 | SIGMAR1 (0.44) | KMT2AMEN1FAAH | |
| SCHEMBL2401137 | 0.73 | TRPV4 (0.49) | KMT2APKM | |
| SCHEMBL2400846 | 0.70 | MEN1 (0.45) | KMT2AMEN1 | |
| SCHEMBL2403707 | 0.68 | SIGMAR1 (0.46) | KMT2AMEN1FAAHPKM | |
| SCHEMBL2403239 | 0.67 | MEN1 (0.47) | KMT2AMEN1FAAH | |
| SCHEMBL15309106 | 0.66 | LMNA (0.51) | KMT2AMEN1NPC1 | |
| SCHEMBL2574163 | 0.66 | PKM (0.50) | KMT2AMEN1NPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401841-B1 | SUBSTITUTED 1-OXA-2,8-DIAZA-SPIRO 4,5]DEC-2-ENE DERIVATIVES AS MEDICAMENTS FOR THE TREATMENT OF PAIN | GRUENENTHAL GMBH (DE) | 2005-08-24 | — | — | EP | claimed |