Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL641811 | 1.00 | TSHR (0.40) | TSHRTET2RECQLHSD17B10MGAM | |
| SCHEMBL20928615 | 0.82 | CA14 (0.45) | TSHRTET2RECQLHSD17B10MGAM | |
| SCHEMBL8556849 | 0.81 | GAA (0.48) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL2317242 | 0.79 | CYP2D6 (0.39) | GAA | |
| SCHEMBL1339541 | 0.79 | CYP2D6 (0.39) | GAA | |
| SCHEMBL2407746 | 0.79 | CYP2D6 (0.39) | GAA | |
| SCHEMBL7401675 | 0.78 | PLA2G2A (0.39) | TSHRTET2RECQLHSD17B10MGAM | |
| SCHEMBL7362273 | 0.78 | TSHR (0.48) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL20814002 | 0.78 | TSHR (0.48) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL2805307 | 0.78 | ALDH1A1 (0.43) | MMEACECPA1ACE2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120215007-A1 | METHOD FOR PREPARING ENANTIOMERICALLY ENRICHED N-CARBOXYANHYDRIDE | SANOFI (FR) | 2012-08-23 | — | — | US | disclosed |
| US-8119813-B2 | Method for preparing enantiomerically enriched N-carboxyanhydride | SANOFI-AVENTIS (FR) | 2012-02-21 | — | — | US | disclosed |
| US-20100113797-A1 | METHOD FOR PREPARING ENANTIOMERICALLY ENRICHED N-CARBOXYANHYDRIDE | SANOFI-AVENTIS (FR) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120215007-A1 | METHOD FOR PREPARING ENANTIOMERICALLY ENRICHED N-CARBOXYANHYDRIDE | DNPEP, NPPA, CPN1 | TSHR 3998/4885TET2 2708/4885RECQL 1828/4885 |
| US-20100113797-A1 | METHOD FOR PREPARING ENANTIOMERICALLY ENRICHED N-CARBOXYANHYDRIDE | DNPEP, NPPA, CPN1 | TSHR 3998/4885TET2 2708/4885RECQL 1828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.