SCHEMBL6418312

SCHEMBL6418312

C#CCCC(=O)OCCOCCOC(=O)CCC#C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.38
TSHR P16473 4/20 0.35
ALDH1A1 P00352 4/20 0.35
TP53 P04637 2/20 0.35
HIF1A Q16665 2/20 0.35
HSD17B10 Q99714 2/20 0.35
ADRA2A P08913 1/20 0.35
ADRA1A P35348 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
GSTP1 P09211 1/20 0.35
MAPT P10636 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
BLM P54132 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TAAR1 Q96RJ0 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6420417 0.93 DGKA (0.41) DGKATSHRALDH1A1HSD17B10ADRA2A
SCHEMBL19821373 0.91 DGKA (0.36) DGKATSHRALDH1A1TP53HIF1A
SCHEMBL19821391 0.91 DGKA (0.44) DGKATSHRALDH1A1HSD17B10ADRA2A
SCHEMBL10009581 0.86 MEN1 (0.42) DGKATSHRHSD17B10ADRA2AADRA1A
SCHEMBL20209799 0.81 TDP1 (0.53) TSHRALDH1A1TDP1MEN1KMT2A
SCHEMBL10124124 0.81 DGKA (0.45) DGKAALDH1A1ADRA2AADRA1AMAPT
SCHEMBL6422929 0.79 TSHR (0.39) DGKATSHRALDH1A1TP53HIF1A
SCHEMBL10011577 0.79 ADRA2A (0.44) DGKATSHRALDH1A1HSD17B10ADRA2A
SCHEMBL10011002 0.79 MEN1 (0.34) DGKAHSD17B10ADRA2AADRA1AGSTP1
SCHEMBL22170234 0.78 TDP1 (0.49) ALDH1A1TDP1MEN1KMT2ATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050281968-A1 Energetic structural material ALLIANT TECHSYSTEMS INC. (US) 2005-12-22 US claimed
US-20050281968-A1 Energetic structural material ALLIANT TECHSYSTEMS INC. (US) 2005-12-22 US disclosed