Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22170234 | 0.96 | TDP1 (0.49) | TDP1ALDH1A1TAAR1SMN1; SMN2NAAA | |
| SCHEMBL16594784 | 0.86 | TDP1 (0.65) | TDP1ALDH1A1SMN1; SMN2NAAALMNA | |
| SCHEMBL3877532 | 0.85 | ALDH1A1 (0.58) | TDP1ALDH1A1TAAR1LMNAMAPK1 | |
| SCHEMBL16594851 | 0.83 | TDP1 (0.61) | TDP1ALDH1A1SMN1; SMN2NAAALMNA | |
| SCHEMBL21184519 | 0.83 | TDP1 (0.61) | TDP1ALDH1A1SMN1; SMN2NAAALMNA | |
| SCHEMBL16594584 | 0.83 | TDP1 (0.61) | TDP1ALDH1A1SMN1; SMN2NAAALMNA | |
| SCHEMBL19825599 | 0.82 | TDP1 (0.41) | TDP1ALDH1A1TAAR1SMN1; SMN2LMNA | |
| SCHEMBL17955285 | 0.82 | TDP1 (0.62) | TDP1ALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL6418312 | 0.81 | DGKA (0.38) | TDP1ALDH1A1TAAR1KMT2AMEN1 | |
| SCHEMBL23819858 | 0.80 | TDP1 (0.61) | TDP1ALDH1A1SMN1; SMN2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10556018-B2 | Compositions and methods for delivery of agents | ARES CAPITAL CORPORATION, AS AGENT | 2020-02-11 | — | — | US | disclosed |
| US-20190117798-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | MODERNATX, INC. (US) | 2019-04-25 | — | — | US | disclosed |
| US-20180147298-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | MODERNATX, INC. (US) | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190117798-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | HDLBP, APOB, TSG101 | TDP1 753/4885ALDH1A1 3952/4885TAAR1 4130/4885 |
| US-10556018-B2 | Compositions and methods for delivery of agents | HDLBP, APOB, TSG101 | TDP1 753/4885ALDH1A1 3952/4885TAAR1 4130/4885 |
| US-20180147298-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | HDLBP, APOB, TSG101 | TDP1 753/4885ALDH1A1 3952/4885TAAR1 4130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.