Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634827 | 0.82 | C5AR1 (0.43) | C5AR1 | |
| SCHEMBL6418644 | 0.78 | TRPM8 (0.42) | C5AR1 | |
| SCHEMBL27639035 | 0.76 | ALDH1A1 (0.60) | MEN1KMT2ABACE1 | |
| SCHEMBL4634472 | 0.75 | SLC6A4 (0.61) | — | |
| Hydrochloric Acid SCHEMBL4666549 | 0.74 | SLC6A4 (0.60) | — | |
| SCHEMBL13696796 | 0.73 | USP30 (0.52) | GPR119USP30MEN1KMT2A | |
| SCHEMBL1449082 | 0.73 | HPGD (0.48) | GPR119MEN1KMT2A | |
| SCHEMBL14450372 | 0.72 | HPGD (0.46) | GPR119USP30 | |
| SCHEMBL13932868 | 0.72 | HTR2A (0.52) | GPR119USP30MEN1KMT2A | |
| SCHEMBL16112711 | 0.72 | KDM4E (0.58) | GPR119KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014789-A1 | Amide derivatives as selective serotonin re-uptake inhibitors | PFIZER INC | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014789-A1 | Amide derivatives as selective serotonin re-uptake inhibitors | SLC6A4, HTR3C, HTR3A | GPR119 773/4885USP30 4245/4885MEN1 2033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.