Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 2/20 | 0.59 |
| ▸ | ALPL | P05186 | 2/20 | 0.59 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.59 |
| ▸ | XIAP | P98170 | 2/20 | 0.59 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL509030 | 0.82 | ENPP3 (0.55) | ENPP3ALPLENPP1XIAPIKBKB | |
| SCHEMBL4239165 | 0.82 | ENPP3 (0.59) | ENPP3ALPLENPP1XIAPMAPT | |
| SCHEMBL4104852 | 0.78 | ENPP3 (0.55) | ENPP3ALPLENPP1XIAPMAPT | |
| SCHEMBL4235277 | 0.74 | AR (0.57) | ENPP3ALPLENPP1XIAPMAPT | |
| SCHEMBL4881284 | 0.73 | MEN1 (0.79) | MAPTMEN1KMT2AALOX12LMNA | |
| SCHEMBL509165 | 0.72 | KCNH2 (0.58) | ENPP3ALPLENPP1XIAPMAPT | |
| SCHEMBL4879474 | 0.72 | MEN1 (0.77) | MAPTMEN1KMT2AALOX12LMNA | |
| SCHEMBL6264652 | 0.71 | FPR2 (0.50) | ENPP3ALPLENPP1XIAPFPR2 | |
| SCHEMBL20489253 | 0.71 | ENPP3 (0.50) | ENPP3ALPLENPP1XIAPFPR2 | |
| SCHEMBL24962586 | 0.68 | IKBKB (0.68) | IKBKBMAP3K14MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050119246-A1 | 2-(4-{[1-(2,2-dimethylpropanoyl)-4-piperidinyl]methyl}-3,5-dimethyl-1H-pyrazol-1-yl)-1-methylethylcarbamate; appetite suppressants; obesity, diabetes, feeding behavior, bulimia, anorexia nervosa and premenstrual tension; side effect reduction | BAYER PHARMACEUTICALS CORPORATION (US) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119246-A1 | 2-(4-{[1-(2,2-dimethylpropanoyl)-4-piperidinyl]methyl}-3,5-dimethyl-1H-pyrazol-1-yl)-1-methylethylcarbamate; appetite suppressants; obesity, diabetes, feeding behavior, bulimia, anorexia nervosa and premenstrual tension; side effect reduction | HTR2C, GPR119, HTR2B | ENPP3 3164/4885ALPL 4116/4885ENPP1 3607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.