Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BCL9 | O00512 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | GPR183 | P32249 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6420512 | 0.88 | GRIN2B (0.40) | FAAHMAPT | |
| SCHEMBL6419465 | 0.87 | PDK2 (0.36) | HRH3PTGDR2MAPTPDK2P2RX7 | |
| SCHEMBL6423885 | 0.86 | PTGDR2 (0.37) | PTGDR2FAAHPDK2P2RX7GPR183 | |
| SCHEMBL6421015 | 0.85 | GRIN2B (0.38) | MEN1KMT2APDK2NPC1RAB9A | |
| SCHEMBL6419564 | 0.85 | HRH3 (0.39) | HRH3PTGDR2MEN1KMT2AFAAH | |
| SCHEMBL6420101 | 0.84 | KDM4E (0.38) | MEN1KMT2AFAAHMAPTNPC1 | |
| SCHEMBL6422626 | 0.84 | PTGDR2 (0.37) | PTGDR2MEN1KMT2APDK2NPC1 | |
| SCHEMBL6420064 | 0.83 | GRIN2B (0.38) | PTGDR2MEN1KMT2AMAPTPDK2 | |
| SCHEMBL6423530 | 0.82 | PTGDR2 (0.36) | PTGDR2MEN1KMT2AMAPTPDK2 | |
| SCHEMBL6420086 | 0.79 | KMT2A (0.35) | PTGDR2MEN1KMT2AMAPTPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908926-B1 | Substituted imidazoles, their preparation and use | NOVO NORDISK A/S (DK) | 2005-06-21 | — | — | US | disclosed |
| EP-1173438-A1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000063208-A1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-10-26 | — | — | WO | disclosed |