Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6423530 | 0.85 | PTGDR2 (0.36) | KMT2AALDH1A1MEN1MAPTPDK2 | |
| SCHEMBL6422626 | 0.83 | PTGDR2 (0.37) | KMT2AALDH1A1MEN1TSHRKDM4E | |
| SCHEMBL6420064 | 0.83 | GRIN2B (0.38) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL6422386 | 0.82 | CD274 (0.42) | — | |
| SCHEMBL6422956 | 0.80 | CHRM5 (0.42) | KMT2AALDH1A1MEN1KDM4EHTT | |
| SCHEMBL6422607 | 0.79 | P2RX7 (0.43) | ALDH1A1MAPTPDK2PTGDR2 | |
| SCHEMBL6419465 | 0.79 | PDK2 (0.36) | MAPTPDK2PTGDR2NPC1 | |
| SCHEMBL6419627 | 0.79 | HRH3 (0.35) | KMT2AMEN1MAPTPDK2HPGD | |
| SCHEMBL6420101 | 0.78 | KDM4E (0.38) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL6420047 | 0.78 | PTGDR2 (0.37) | KMT2AMEN1PDK2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908926-B1 | Substituted imidazoles, their preparation and use | NOVO NORDISK A/S (DK) | 2005-06-21 | — | — | US | disclosed |
| EP-1173438-A1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000063208-A1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-10-26 | — | — | WO | disclosed |