SCHEMBL10535596

SCHEMBL10535596

COC(=O)C(NC(=O)OCc1ccccc1)C(C)C

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 1/20 0.62
CTSL P07711 4/20 0.62
CTSB P07858 4/20 0.62
CTSS P25774 3/20 0.62
CTSK P43235 3/20 0.62
KYNU Q16719 1/20 0.57
ATM Q13315 1/20 0.57
ELANE P08246 2/20 0.56
PRTN3 P24158 1/20 0.56
ALDH1A1 P00352 1/20 0.55
ALOX15 P16050 1/20 0.55
CASP3 P42574 2/20 0.55
CA2 P00918 1/20 0.55
CA5A P35218 1/20 0.55
CASP1 P29466 1/20 0.55
CASP7 P55210 1/20 0.55
CASP6 P55212 1/20 0.55
CASP8 Q14790 1/20 0.55
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10535601 1.00 TRPM8 (0.62) TRPM8CTSLCTSBCTSSCTSK
SCHEMBL28892051 1.00 TRPM8 (0.62) TRPM8CTSLCTSBCTSSCTSK
SCHEMBL3210676 0.94 CTSB (0.60) TRPM8CTSLCTSBCTSSCTSK
SCHEMBL13823620 0.94 CTSB (0.60) TRPM8CTSLCTSBCTSSCTSK
SCHEMBL1908598 0.91 CTSK (0.62) CTSLCTSBCTSSCTSKATM
SCHEMBL15317910 0.90 CTSL (0.68) TRPM8CTSLCTSBCTSSCTSK
SCHEMBL8105214 0.90 CTSL (0.68) TRPM8CTSLCTSBCTSSCTSK
SCHEMBL15878934 0.90 CTSL (0.68) TRPM8CTSLCTSBCTSSCTSK
SCHEMBL9782142 0.90 CTSL (0.68) TRPM8CTSLCTSBCTSSCTSK
SCHEMBL15889688 0.90 CTSL (0.68) TRPM8CTSLCTSBCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111334265-A Clay mineral nano hydrogel plugging agent and water-based drilling fluid 西南石油大学 2020-06-26 CN disclosed
CN-105037468-A Preparation method of antivirus composition and application of intermediate of antivirus composition INHIBITEX INC 2015-11-11 CN disclosed
CN-102443032-B Process for preparing antiviral composition and use of intermediate thereof INHIBITEX INC 2015-07-22 CN disclosed
US-4837349-A Tertiary-butyldimethylsilyl carbamate derivative and process for producing the same SUNTORY LIMITED (JP) 1989-06-06 US disclosed