SCHEMBL6420527

SCHEMBL6420527

CCCCCCCCOc1ccc(/C=N\c2ccccc2C#N)cc1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.54
FAAH O00519 8/20 0.44
LTA4H P09960 1/20 0.43
ALDH1A1 P00352 4/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
KDM4E B2RXH2 2/20 0.43
HPGD P15428 2/20 0.43
HTT P42858 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
MAPT P10636 1/20 0.42
NR5A1 Q13285 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6369640 1.00 LMNA (0.54) LMNAFAAHLTA4HALDH1A1MEN1
SCHEMBL6422393 0.96 LMNA (0.58) LMNAFAAHLTA4HALDH1A1MEN1
SCHEMBL8773631 0.86 LMNA (0.61) LMNAALDH1A1MEN1KMT2AKDM4E
SCHEMBL8773627 0.86 LMNA (0.61) LMNAALDH1A1MEN1KMT2AKDM4E
SCHEMBL8624249 0.82 LMNA (0.57) LMNAFAAHALDH1A1KDM4EHPGD
SCHEMBL8619952 0.79 LMNA (0.66) LMNAALDH1A1MEN1KMT2AKDM4E
SCHEMBL29103296 0.79 NR5A1 (0.46) FAAHLTA4HMEN1KMT2ANR5A1
SCHEMBL10334267 0.79 SMN1; SMN2 (0.60) LMNAALDH1A1MEN1KMT2AKDM4E
SCHEMBL4541633 0.79 ALDH1A1 (0.51) LMNAFAAHALDH1A1MEN1KMT2A
SCHEMBL269185 0.79 ALDH1A1 (0.51) LMNAFAAHALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050041196-A1 Display apparatus SHARP KABUSHIKI KAISHA (JP) 2005-02-24 US disclosed