Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773627 | 1.00 | LMNA (0.61) | LMNAALDH1A1MEN1KMT2AGAA | |
| SCHEMBL6422393 | 0.89 | LMNA (0.58) | LMNAALDH1A1MEN1KMT2AGAA | |
| SCHEMBL6420527 | 0.86 | LMNA (0.54) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6369640 | 0.86 | LMNA (0.54) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8619952 | 0.84 | LMNA (0.66) | LMNAALDH1A1MEN1KMT2AGAA | |
| SCHEMBL11773408 | 0.84 | MAOB (0.47) | LMNAALDH1A1MEN1KMT2AGAA | |
| SCHEMBL16620671 | 0.79 | LMNA (0.71) | LMNAALDH1A1MEN1KMT2AGAA | |
| SCHEMBL16620673 | 0.79 | LMNA (0.71) | LMNAALDH1A1MEN1KMT2AGAA | |
| SCHEMBL11587787 | 0.78 | LMNA (0.75) | LMNAALDH1A1MEN1KMT2AGAA | |
| SCHEMBL11796171 | 0.78 | LMNA (0.75) | LMNAALDH1A1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3984343-A | Liquid crystal mixtures with selectively variable dielectric anisotropies | GENERAL ELECTRIC COMPANY (US) | 1976-10-05 | — | — | US | claimed |
| EP-0803525-A2 | Chiral anisotropic thermosets (cat) in polymer stabilized liquid crystals | Sniaricerche S.C.P.A. (IT) | 1997-10-29 | — | — | EP | disclosed |
| US-3984343-A | Liquid crystal mixtures with selectively variable dielectric anisotropies | GENERAL ELECTRIC COMPANY (US) | 1976-10-05 | — | — | US | disclosed |