Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TYR | P14679 | 3/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | APEX1 | P27695 | 2/20 | 0.36 |
| ▸ | RAD52 | P43351 | 2/20 | 0.36 |
| ▸ | GAPDH | P04406 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11321268 | 0.82 | ALOX5 (0.63) | HMGCRMEN1KMT2ATDP1MAPT | |
| SCHEMBL15868713 | 0.82 | ALOX5 (0.63) | MEN1KMT2ATDP1MAPTTYR | |
| SCHEMBL15868714 | 0.82 | ALOX5 (0.63) | MEN1KMT2ATDP1MAPTTYR | |
| Butane SCHEMBL27757522 | 0.81 | MAPT (0.42) | HMGCRMEN1KMT2ATDP1MAPT | |
| SCHEMBL10790730 | 0.81 | TYR (0.61) | HMGCRMEN1KMT2ATDP1MAPT | |
| SCHEMBL1760537 | 0.81 | HMGCR (0.64) | HMGCRMEN1KMT2ATDP1MAPT | |
| SCHEMBL28397980 | 0.80 | ALOX5 (0.61) | MEN1KMT2ATDP1MAPTTYR | |
| SCHEMBL5675974 | 0.79 | ALOX5 (0.55) | HMGCRMEN1KMT2ATDP1MAPT | |
| SCHEMBL14151092 | 0.79 | LMNA (0.59) | MEN1KMT2ATDP1MAPTTYR | |
| SCHEMBL143956 | 0.79 | ALOX5 (0.64) | HMGCRMEN1KMT2ATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050277700-A1 | Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same | MCNEIL-PPC, INC | 2005-12-15 | — | — | US | disclosed |
| US-20040199028-A1 | Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same | MCNEIL-PPC, INC | 2004-10-07 | — | — | US | disclosed |
| US-20030139478-A1 | Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same | HARPER D SCOTT | 2003-07-24 | — | — | US | disclosed |
| WO-2003053897-A1 | NON-HALOGENATED HYDROXYALKYL-SUBSTITUTED PHENOL COMPOUNDS, ANTIMICROBIAL COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME | WARNER-LAMBERT COMPANY LLC (US) | 2003-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277700-A1 | Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same | HDHD5, TYR, NONO | HMGCR 2590/4885MEN1 4694/4885KMT2A 2995/4885 |
| US-20030139478-A1 | Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same | HDHD5, TYR, NONO | HMGCR 2590/4885MEN1 4694/4885KMT2A 2995/4885 |
| US-20040199028-A1 | Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same | HDHD5, TYR, NONO | HMGCR 2590/4885MEN1 4694/4885KMT2A 2995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.