SCHEMBL4728428

SCHEMBL4728428

O=C(Cl)c1cccc(C(=O)Cl)c1Br

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
ALOX15 P16050 2/20 0.50
TSHR P16473 1/20 0.38
CES2 O00748 2/20 0.37
CES1 P23141 2/20 0.37
BCHE P06276 1/20 0.34
MMP3 P08254 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
PRNP P04156 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
POLB P06746 1/20 0.33
NR4A1 P22736 1/20 0.33
NR4A2 P43354 1/20 0.33
NR4A3 Q92570 1/20 0.33
PTPN1 P18031 1/20 0.33
AKR1C3 P42330 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MPO P05164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6420545 0.88 ALDH1A1 (0.45) ALDH1A1ALOX15TSHRCES2CES1
SCHEMBL7596116 0.86 ALDH1A1 (0.52) ALDH1A1ALOX15TSHRCES2CES1
SCHEMBL19972048 0.84 MMP2 (0.44) ALDH1A1ALOX15POLBKDM4EGAA
SCHEMBL31315009 0.84 ALDH1A1 (0.44) ALDH1A1ALOX15SMN1; SMN2POLBAKR1C3
SCHEMBL17938254 0.84 ALDH1A1 (0.63) ALDH1A1ALOX15CES2CES1BCHE
SCHEMBL2229478 0.84 ALDH1A1 (0.44) ALDH1A1ALOX15SMN1; SMN2POLBAKR1C3
SCHEMBL27974066 0.84 ALDH1A1 (0.42) ALDH1A1ALOX15TSHRCES2CES1
SCHEMBL27925017 0.80 TAS2R14 (0.53) ALDH1A1ALOX15HDAC8SMN1; SMN2GAA
SCHEMBL27955539 0.80 ALDH1A1 (0.38) ALDH1A1ALOX15TSHRMMP3SMN1; SMN2
SCHEMBL5424186 0.80 CTSD (0.47) ALDH1A1POLBKDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116041957-B Polyimide film and preparation method thereof 吉林高琦聚酰亚胺材料有限公司 2025-03-25 CN disclosed
CN-118653224-A Polyimide fiber and preparation method thereof 长春高琦聚酰亚胺材料有限公司 2024-09-17 CN disclosed
CN-118653305-A Composite polyimide fiber and preparation method thereof 长春高琦聚酰亚胺材料有限公司 2024-09-17 CN disclosed
CN-118638310-A Polyimide powder, preparation method thereof and thermoplastic plastic 长春高琦聚酰亚胺材料有限公司 2024-09-13 CN disclosed
CN-116041957-A Polyimide film and preparation method thereof 长春聚明光电材料有限公司 2023-05-02 CN disclosed
US-20080203013-A1 OXIDATION-RESISTANT COMPOSITE REVERSE OSMOSIS MEMBRANE VONTRON MEMBRANE TECHNOLOGY CO., LTD. (CN) 2008-08-28 US disclosed
WO-2008025259-A1 OXIDATION-RESISTANT COMPOSITE REVERSE OSMOSIS MEMBRANE VONTRON MEMBRANE TECHNOLOGY CO., LTD. (CN) 2008-03-06 WO disclosed
EP-1894614-A1 Oxidation-resistant composite reverse osmosis membrane Vontron Membrane Technology Co Ltd (CN) 2008-03-05 EP disclosed
US-20070015896-A1 Dihydroxy aramid polymers E. I. DU PONT DE NEMOURS AND COMPANY 2007-01-18 US disclosed
WO-2007008889-A2 DIHYDROXY ARAMID POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-01-18 WO disclosed
EP-0376234-B2 Semipermeable membranes based on specified tetrabromobisphenol type polyesters PRAXAIR TECHNOLOGY INC (US) 1999-01-20 EP disclosed
US-5055114-A Gas separation UNION CARBIDE INDUSTRIAL GASES TECHNOLOGY CORPORATION (US) 1991-10-08 US disclosed
EP-0113252-B1 PROCESS FOR PRODUCING BLOCK COPOLYAMIDE TORAY INDUSTRIES, INC. (JP) 1991-08-07 EP disclosed
EP-0376234-A2 Semipermeable membranes based on specified tetrabromobisphenol type polyesters PRAXAIR TECHNOLOGY, INC. (US) 1990-07-04 EP disclosed
US-4507465-A IMPACT STRENGTH TORAY INDUSTRIES, INC. (JP) 1985-03-26 US disclosed
EP-0113252-A2 Process for producing block copolyamide TORAY INDUSTRIES, INC. (JP) 1984-07-11 EP disclosed
US-4101399-A Production of solvent resistant brominated and/or chlorinated aromatic polyester fibrous materials CELANESE CORPORATION (US) 1978-07-18 US disclosed