Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCD | Q05655 | 2/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | PRKCA | P17252 | 1/20 | 0.55 |
| ▸ | CDK2 | P24941 | 4/20 | 0.53 |
| ▸ | CDK4 | P11802 | 3/20 | 0.53 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.53 |
| ▸ | IKBKB | O14920 | 3/20 | 0.53 |
| ▸ | CDK1 | P06493 | 2/20 | 0.53 |
| ▸ | AURKA | O14965 | 2/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.53 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.53 |
| ▸ | PRKCG | P05129 | 1/20 | 0.53 |
| ▸ | LYN | P07948 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KIT | P10721 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18901342 | 0.78 | AURKA (0.69) | PRKCDEGFRCDK2IKBKBCDK1 | |
| SCHEMBL28680535 | 0.78 | CAMK2D (0.55) | PRKCDABL1EGFRPRKCACDK2 | |
| SCHEMBL7470857 | 0.78 | ABL1 (0.63) | PRKCDABL1EGFRPRKCACDK2 | |
| SCHEMBL23281419 | 0.77 | JAK2 (0.53) | JAK2JAK3 | |
| SCHEMBL1593016 | 0.77 | PRKCD (0.79) | PRKCDABL1EGFRPRKCACDK2 | |
| SCHEMBL1448464 | 0.76 | CDK1 (0.56) | PRKCDABL1EGFRPRKCACDK2 | |
| SCHEMBL7463899 | 0.76 | SYK (0.57) | PRKCDABL1EGFRPRKCACDK2 | |
| SCHEMBL1448466 | 0.76 | CDK1 (0.56) | PRKCDABL1EGFRPRKCACDK2 | |
| SCHEMBL27110324 | 0.76 | PRKCD (0.55) | PRKCDABL1EGFRPRKCACDK2 | |
| SCHEMBL15124961 | 0.75 | PRKCD (0.50) | PRKCDABL1EGFRPRKCACDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050080101-A1 | Pyrazoles-pyrimidine fungicides | SYNGENTA CROP PROTECTION, INC. | 2005-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080101-A1 | Pyrazoles-pyrimidine fungicides | DHFR, CYP3A7, CBR3 | PRKCD 3258/4885ABL1 1212/4885EGFR 3914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.