Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ACLY | P53396 | 6/20 | 0.54 |
| ▸ | HTR6 | P50406 | 2/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.49 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6426199 | 0.90 | PTGDR2 (0.58) | LMNAACLYHTR6PTGDR2PTGDR | |
| SCHEMBL3565477 | 0.89 | ACLY (0.57) | LMNAACLYHTR6PTGDR2PTGDR | |
| SCHEMBL6425246 | 0.84 | PTGDR2 (0.67) | LMNAHTR6PTGDR2PTGDRMAPT | |
| SCHEMBL6423753 | 0.83 | ACLY (0.59) | LMNAACLYHTR6PTGDR2PTGDR | |
| SCHEMBL3562004 | 0.81 | PTGDR2 (0.51) | ACLYHTR6PTGDR2PTGDRPPARG | |
| SCHEMBL6440106 | 0.78 | LMNA (0.51) | LMNAACLYHTR6PTGDR2PTGDR | |
| SCHEMBL5273202 | 0.75 | LMNA (0.54) | LMNAACLYHTR6PTGDR2PTGDR | |
| SCHEMBL5330204 | 0.75 | LMNA (0.51) | LMNAACLYHTR6PTGDR2PTGDR | |
| SCHEMBL29839883 | 0.74 | ACLY (0.64) | LMNAACLYHTR6PPARGPPARD | |
| SCHEMBL14953583 | 0.74 | PPARG (0.61) | LMNAACLYHTR6MAPTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567492-B1 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | SUVEN LIFE SCIENCES LTD (IN) | 2013-05-22 | — | — | EP | disclosed |
| EP-1567492-A2 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | Suven Life Sciences Limited (IN) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048328-A2 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |