SCHEMBL6426199

SCHEMBL6426199

Cc1c(O)c2cc(Cl)ccc2n1S(=O)(=O)c1ccc(F)cc1

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 9/20 0.58
PTGDR Q13258 5/20 0.58
ACLY P53396 3/20 0.52
HTR6 P50406 5/20 0.47
MAPT P10636 1/20 0.47
LMNA P02545 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6420835 0.90 LMNA (0.57) PTGDR2PTGDRACLYHTR6MAPT
SCHEMBL3565477 0.87 ACLY (0.57) PTGDR2PTGDRACLYHTR6MAPT
SCHEMBL6425246 0.84 PTGDR2 (0.67) PTGDR2PTGDRHTR6MAPTLMNA
SCHEMBL3558278 0.82 PTGDR2 (0.68) PTGDR2PTGDRACLYHTR6LMNA
SCHEMBL6421393 0.81 ACLY (0.53) PTGDR2PTGDRACLYHTR6
SCHEMBL14953444 0.76 ACLY (0.55) PTGDR2PTGDRACLYHTR6LMNA
SCHEMBL3557713 0.76 PTGDR2 (0.49) PTGDR2PTGDRHTR6
SCHEMBL947210 0.76 HTR6 (0.74) PTGDR2PTGDRHTR6
SCHEMBL6531234 0.74 PTGDR2 (1.00) PTGDR2PTGDR
SCHEMBL6423753 0.73 ACLY (0.59) PTGDR2PTGDRACLYHTR6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1567492-B1 N-ARYLSULFONYL-3-AMINOALKOXYINDOLES SUVEN LIFE SCIENCES LTD (IN) 2013-05-22 EP disclosed
EP-1567492-A2 N-ARYLSULFONYL-3-AMINOALKOXYINDOLES Suven Life Sciences Limited (IN) 2005-08-31 EP disclosed
WO-2004048328-A2 N-ARYLSULFONYL-3-AMINOALKOXYINDOLES SUVEN LIFE SCIENCES LIMITED (IN) 2004-06-10 WO disclosed