Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803619 | 0.87 | RECQL (0.60) | RECQLHTTSMN1; SMN2KMT2APKM | |
| SCHEMBL8437521 | 0.85 | L3MBTL1 (0.56) | RECQLHTTSMN1; SMN2KMT2APKM | |
| SCHEMBL513249 | 0.85 | L3MBTL1 (0.56) | RECQLHTTSMN1; SMN2KMT2APKM | |
| SCHEMBL513250 | 0.85 | L3MBTL1 (0.56) | RECQLHTTSMN1; SMN2KMT2APKM | |
| Hydrochloric Acid SCHEMBL8439652 | 0.84 | TBXAS1 (0.55) | RECQLHTTSMN1; SMN2KMT2APKM | |
| Hydrochloric Acid SCHEMBL8439653 | 0.84 | TBXAS1 (0.55) | RECQLHTTSMN1; SMN2KMT2APKM | |
| SCHEMBL27567307 | 0.83 | ALDH1A1 (0.53) | ALDH1A1RECQLHTTSMN1; SMN2KMT2A | |
| SCHEMBL7371606 | 0.83 | ALDH1A1 (0.53) | ALDH1A1RECQLHTTSMN1; SMN2KMT2A | |
| SCHEMBL106076 | 0.81 | MAPT (0.67) | ALDH1A1KMT2AL3MBTL1POLBMAPT | |
| SCHEMBL106075 | 0.81 | MAPT (0.67) | ALDH1A1KMT2AL3MBTL1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983267-B1 | AMIDOAROMATIC RING SULFONAMIDE HYDROXAMIC ACID COMPOUNDS | PHARMACIA CORP (US) | 2005-01-26 | — | — | EP | disclosed |
| US-6451791-B1 | Amidoaromatic ring sulfonamide hydroxamic acid compounds | MONSANTO COMPANY | 2002-09-17 | — | — | US | disclosed |
| EP-0983267-A1 | AMIDOAROMATIC RING SULFONAMIDE HYDROXAMIC ACID COMPOUNDS | MONSANTO COMPANY (US) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998039329-A1 | AMIDOAROMATIC RING SULFONAMIDE HYDROXAMIC ACID COMPOUNDS | MONSANTO COMPANY (US) | 1998-09-11 | — | — | WO | disclosed |