SCHEMBL6421372

SCHEMBL6421372

NCn1c(=O)cc[nH]c1=O

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HASPIN Q8TF76 1/20 0.31
ADRA1D P25100 1/20 0.31
ADRA1A P35348 1/20 0.31
ADRA1B P35368 1/20 0.31
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2930015 0.83 HASPIN (0.35) HASPINADRA1DADRA1AADRA1B
SCHEMBL4348692 0.82 ADRA1D (0.37) ADRA1DADRA1AADRA1B
SCHEMBL17371770 0.80 HASPIN (0.43) HASPINADRA1DADRA1AADRA1BHPGD
SCHEMBL5792155 0.79 MMP2 (0.34) ALDH1A1CYP3A4
SCHEMBL3235865 0.79 ADRA1D (0.37) HASPINADRA1DADRA1AADRA1B
SCHEMBL338056 0.78 TYMP (0.32) ADRA1DADRA1AADRA1B
SCHEMBL8377755 0.78 TYMP (0.32) ADRA1DADRA1AADRA1B
SCHEMBL8377767 0.78 ADRA1D (0.31) ADRA1DADRA1AADRA1B
SCHEMBL1923337 0.78 CYP1A2 (0.44) ALDH1A1CYP3A4
SCHEMBL10618040 0.78 ADRA1D (0.33) ADRA1DADRA1AADRA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5830867-A Hemoregulatory peptides for stimulating the myelopoietic system SMITHKLINE BEECHAM CORPORATION (US) 1998-11-03 US claimed
EP-0701446-A4 HEMOREGULATORY PEPTIDES SMITHKLINE BEECHAM CORP (US) 1997-04-23 EP claimed
EP-0701446-A1 HEMOREGULATORY PEPTIDES SMITHKLINE BEECHAM CORPORATION (US) 1996-03-20 EP claimed
WO-1994027627-A1 HEMOREGULATORY PEPTIDES SMITHKLINE BEECHAM CORPORATION (US) 1994-12-08 WO claimed
US-12545712-B2 C3d cellular and acellular vaccines for the prevention and treatment of cancer THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2026-02-10 US disclosed
US-20250382612-A1 COMPOSITIONS AND METHODS FOR TREATING DISEASES ASSOCIATED WITH PATHOGENIC FUS VARIANTS THE PERRON INSTITUTE FOR NEUROLOGICAL AND TRANSLATIONAL SCIENCE LIMITED (AU) 2025-12-18 US disclosed
US-12234448-B2 Purification of nucleic acids using titanium oxides ABBOTT MOLECULAR INC. 2025-02-25 US disclosed
US-20230193240-A1 PURIFICATION OF NUCLEIC ACIDS USING COPPER-TITANIUM OXIDES ABBOTT MOLECULAR INC. 2023-06-22 US disclosed
US-11608496-B2 Purification of nucleic acids using copper-titanium oxides ABBOTT MOLECULAR INC. (US) 2023-03-21 US disclosed
US-20220242924-A1 C3D CELLULAR AND ACELLULAR VACCINES FOR THE PREVENTION AND TREATMENT OF CANCER THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2022-08-04 US disclosed
EP-3988658-A1 PURIFICATION OF NUCLEIC ACIDS USING COPPER-TITANIUM OXIDES Abbott Molecular Inc. (US) 2022-04-27 EP disclosed
US-11313001-B2 Compositions and methods for detection of microorganisms THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2022-04-26 US disclosed
WO-1999026960-A2 GENES ENCODING FRIZZLED-LIKE PROTEINS MILLENNIUM PHARMACEUTICALS, INC. (US) 1999-06-03 WO disclosed
WO-1999024610-A1 NOVEL GENES ENCODING TRANSPORTER-LIKE MOLECULES MILLENNIUM PHARMACEUTICALS, INC. (US) 1999-05-20 WO disclosed
WO-1999007850-A1 TANGO-71, TANGO-73, TANGO-74, TANGO-76, AND TANGO-83 NUCLEIC ACID MOLECULES AND POLYPEPTIDES MILLENNIUM BIOTHERAPEUTICS, INC. (US) 1999-02-18 WO disclosed
WO-1999002545-A2 ANTIGEN BINDING FRAGMENTS, DESIGNATED 4B5, THAT SPECIFICALLY DETECT CANCER CELLS, NUCLEOTIDES ENCODING THE FRAGMENTS, AND USE THEREOF FOR THE PROPHYLAXIS AND DETECTION OF CANCERS NOVOPHARM BIOTECH INC. (CA) 1999-01-21 WO disclosed
US-5830867-A Hemoregulatory peptides for stimulating the myelopoietic system SMITHKLINE BEECHAM CORPORATION (US) 1998-11-03 US disclosed
EP-0701446-A4 HEMOREGULATORY PEPTIDES SMITHKLINE BEECHAM CORP (US) 1997-04-23 EP disclosed
EP-0701446-A1 HEMOREGULATORY PEPTIDES SMITHKLINE BEECHAM CORPORATION (US) 1996-03-20 EP disclosed
WO-1994027627-A1 HEMOREGULATORY PEPTIDES SMITHKLINE BEECHAM CORPORATION (US) 1994-12-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545712-B2 C3d cellular and acellular vaccines for the prevention and treatment of cancer C5AR2, C3AR1, CFD HASPIN 1791/4885ADRA1D 4041/4885ADRA1A 4801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.