Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529918 | 0.74 | PTGDR2 (0.41) | PDK1PDK2PDK3PDK4PTGDR2 | |
| SCHEMBL7532232 | 0.74 | PDK1 (0.40) | P2RX7PDK1PDK2PDK3PDK4 | |
| SCHEMBL5645729 | 0.72 | DPP4 (0.55) | P2RX7DPP4DPP8DPP7 | |
| SCHEMBL7528877 | 0.72 | PDK1 (0.39) | P2RX7PDK1PDK2PDK3PDK4 | |
| SCHEMBL6421015 | 0.66 | GRIN2B (0.38) | PDK2NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| Oxalic Acid SCHEMBL6421435 | 0.66 | AOC3 (0.55) | PDK1PDK2PDK3PDK4PTGDR2 | |
| SCHEMBL6420512 | 0.65 | GRIN2B (0.40) | FAAHGRIN2B | |
| SCHEMBL7502819 | 0.65 | P2RX7 (0.42) | P2RX7DPP4DPP8DPP7PDK2 | |
| SCHEMBL11474322 | 0.65 | SMN1; SMN2 (0.41) | PDK1PDK2PDK3PDK4NPC1 | |
| SCHEMBL27144 | 0.63 | ALDH1A1 (0.68) | NPC1RAB9ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908926-B1 | Substituted imidazoles, their preparation and use | NOVO NORDISK A/S (DK) | 2005-06-21 | — | — | US | disclosed |