Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL118020 | 0.72 | MAOA (0.40) | MAOAMAOBFTOKDM4EALDH1A1 | |
| SCHEMBL3295735 | 0.71 | ALDH1A1 (0.37) | MAOAMAOBFTOKDM4EALDH1A1 | |
| SCHEMBL6421632 | 0.70 | MAOB (0.35) | MAOAMAOBFTODYRK1A | |
| SCHEMBL6708105 | 0.67 | ALDH1A1 (0.43) | MAOAMAOBFTOKDM4EALDH1A1 | |
| SCHEMBL10746966 | 0.66 | KDM4E (0.40) | KDM4EALDH1A1HPGD | |
| SCHEMBL5229303 | 0.66 | KDM4E (0.40) | MAOAMAOBFTOKDM4EALDH1A1 | |
| SCHEMBL29588824 | 0.66 | MAPK10 (0.42) | MAOAMAOBFTOKDM4EALDH1A1 | |
| SCHEMBL4495841 | 0.66 | MAPK10 (0.42) | MAOAMAOBFTOKDM4EALDH1A1 | |
| SCHEMBL28747394 | 0.65 | RCE1 (0.35) | MAOAMAOBFTOKDM4EALDH1A1 | |
| SCHEMBL6350173 | 0.63 | KDM4E (0.41) | KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1297556-C | New benzo[b]chromeno-naphthyridin-7-one and pyrano[2',3':7,8] quino[2,3-b]quinoxalin-7-one compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2007-01-31 | — | — | CN | disclosed |
| EP-1561753-A2 | Benzo[b]chromenonapthyridin-7-one and pyrano[2',3':7,8]quino[2,3-b]Quinoxalin-7-one derivatives, process of synthesis, pharmaceutical compositions and their antitumoral properties for the treatment of cancer | Les Laboratoires Servier (FR) | 2005-08-10 | — | — | EP | disclosed |