Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.32 |
| ▸ | MEN1 | O00255 | 5/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5153688 | 0.78 | LMNA (0.44) | MAOAMAOBFTONFKB1ALDH1A1 | |
| SCHEMBL6708105 | 0.73 | ALDH1A1 (0.43) | MAOAMAOBFTOALDH1A1KDM4E | |
| SCHEMBL10746966 | 0.72 | KDM4E (0.40) | ALDH1A1KDM4EHPGDLMNAKMT2A | |
| SCHEMBL6421629 | 0.72 | MAOA (0.33) | MAOAMAOBFTOALDH1A1KDM4E | |
| SCHEMBL5407353 | 0.71 | POLB (0.44) | MAOAMAOBFTOALDH1A1KDM4E | |
| SCHEMBL29588824 | 0.71 | MAPK10 (0.42) | MAOAMAOBFTOALDH1A1KDM4E | |
| SCHEMBL4495841 | 0.71 | MAPK10 (0.42) | MAOAMAOBFTOALDH1A1KDM4E | |
| SCHEMBL4725062 | 0.71 | SMN1; SMN2 (0.33) | MAOAMAOBFTONFKB1ALDH1A1 | |
| SCHEMBL28747394 | 0.71 | RCE1 (0.35) | MAOAMAOBFTONFKB1ALDH1A1 | |
| SCHEMBL3295735 | 0.69 | ALDH1A1 (0.37) | MAOAMAOBFTOALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116036083-B | Application of pyranoquinolinone compounds in preparation of medicines for treating cervical cancer | 江西省林业科学院 | 2023-06-02 | — | — | CN | claimed |
| CN-116036083-A | Application of pyranoquinolinone compounds in preparation of medicines for treating cervical cancer | 江西省林业科学院 | 2023-05-02 | — | — | CN | claimed |
| US-20210251961-A1 | COMPOSITIONS FOR DELIVERY OF THERAPEUTICS INTO THE EYES AND METHODS FOR MAKING AND USING SAME | ALLERGAN INC (US) | 2021-08-19 | — | — | US | claimed |
| EP-1654002-B1 | COMPOSITIONS FOR DELIVERY OF THERAPEUTICS INTO THE EYES AND METHODS FOR MAKING AND USING THE SAME | ALLERGAN INC (US) | 2009-10-07 | — | — | EP | claimed |
| EP-1654002-A2 | COMPOSITIONS FOR DELIVERY OF THERAPEUTICS INTO THE EYES AND METHODS FOR MAKING AND USING THE SAME | Allergan, Inc. (US) | 2006-05-10 | — | — | EP | claimed |
| WO-2005014046-A2 | COMPOSITIONS FOR DELIVERY OF THERAPEUTICS INTO THE EYES AND METHODS FOR MAKING AND USING THE SAME | ALLERGAN, INC. (US) | 2005-02-17 | — | — | WO | claimed |
| US-20050031697-A1 | Compositions for delivery of therapeutics into the eyes and methods for making and using same | ALLERGAN, INC. (US) | 2005-02-10 | — | — | US | claimed |
| CN-114891011-B | Preparation method of medical intermediate 2-amino-tetrahydropyran [3,2-c ] quinoline-5-one derivative | 南京苏亦欣医药科技有限公司 | 2025-01-17 | — | — | CN | disclosed |
| CN-118496286-A | Chemical synthesis method of vibrio vulnificus organism type 2A serotype O-antigen disaccharide fragment | 江南大学 | 2024-08-16 | — | — | CN | disclosed |
| CN-116036083-B | Application of pyranoquinolinone compounds in preparation of medicines for treating cervical cancer | 江西省林业科学院 | 2023-06-02 | — | — | CN | disclosed |
| CN-116036083-B | Application of pyranoquinolinone compounds in preparation of medicines for treating cervical cancer | 江西省林业科学院 | 2023-06-02 | — | — | CN | disclosed |
| CN-116036083-B | Application of pyranoquinolinone compounds in preparation of medicines for treating cervical cancer | 江西省林业科学院 | 2023-06-02 | — | — | CN | disclosed |
| CN-116036083-A | Application of pyranoquinolinone compounds in preparation of medicines for treating cervical cancer | 江西省林业科学院 | 2023-05-02 | — | — | CN | disclosed |
| US-4760072-A | Crystalline and contains bound water; treats reversible obstructive condition of airways in a mammal | FISONS, PLC (GB) | 1988-07-26 | — | — | US | disclosed |
| EP-0030423-B1 | A PROCESS FOR THE PRODUCTION OF 1,4-DIHYDRO-4-OXO-QUINOLINE-2-CARBOXYLIC ACIDS, OR SALTS, ESTERS OR AMIDES THEREOF AND INTERMEDIATES THEREFOR | FISONS plc (GB) | 1985-02-13 | — | — | EP | disclosed |
| US-4474787-A | 7,6 Dioxo-4H,6H-pyrano[3,2-g]quinoline dicarboxylic acids and anti-allergic use thereof | FISONS LIMITED (GB) | 1984-10-02 | — | — | US | disclosed |
| US-4419352-A | ANTIALLERGENS; ANTI SECRETORY AGENTS; MUCUS | FISONS LIMITED (GB) | 1983-12-06 | — | — | US | disclosed |
| US-4414416-A | Certain diacetyl-amino-phenolic derivatives | FISONS LIMITED (GB) | 1983-11-08 | — | — | US | disclosed |
| US-4328341-A | Process for preparing certain pyrano[3,2-g]quinoline 2,8-dicarboxylates and 4-oxo-quinoline-2-carboxylates | FISONS LIMITED (GB) | 1982-05-04 | — | — | US | disclosed |
| EP-0030423-A1 | A process for the production of 1,4-dihydro-4-oxo-quinoline-2-carboxylic acids, or salts, esters or amides thereof and intermediates therefor | FISONS plc (GB) | 1981-06-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050031697-A1 | Compositions for delivery of therapeutics into the eyes and methods for making and using same | MUC1, EPCAM, MYOC | MAOA 3233/4885MAOB 3737/4885FTO 4858/4885 |
| US-20210251961-A1 | COMPOSITIONS FOR DELIVERY OF THERAPEUTICS INTO THE EYES AND METHODS FOR MAKING AND USING SAME | MUC1, EPCAM, MYOC | MAOA 3324/4885MAOB 3764/4885FTO 4860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.