Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6421667 | 1.00 | KMT2A (0.50) | KMT2ALMNAMEN1ALDH1A1CHRM1 | |
| SCHEMBL16540048 | 0.84 | KMT2A (0.49) | KMT2ALMNAMEN1ALDH1A1CHRM1 | |
| SCHEMBL16540050 | 0.84 | KMT2A (0.49) | KMT2ALMNAMEN1ALDH1A1CHRM1 | |
| SCHEMBL10568467 | 0.81 | TDP1 (0.52) | KMT2ACYP2D6TDP1 | |
| SCHEMBL10568471 | 0.81 | TDP1 (0.52) | KMT2ACYP2D6TDP1 | |
| SCHEMBL22660166 | 0.79 | KMT2A (0.55) | KMT2ALMNAMEN1ALDH1A1CHRM1 | |
| SCHEMBL14288482 | 0.79 | HDAC1 (0.50) | KMT2ALMNAMEN1ALDH1A1CHRM1 | |
| SCHEMBL4630812 | 0.78 | MTNR1A (0.48) | ALDH1A1TDP1NPSR1L3MBTL1HDAC1 | |
| SCHEMBL14288483 | 0.78 | HDAC1 (0.52) | KMT2ALMNAMEN1ALDH1A1CHRM1 | |
| SCHEMBL2773353 | 0.76 | CYP19A1 (0.56) | KMT2ALMNAALDH1A1CYP2D6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015028960-A1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES AS GPR AGONISTS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2015-03-05 | — | — | WO | disclosed |
| US-6972294-B1 | Compounds, their preparation and use | NOVO NORDISK, A/S (DK) | 2005-12-06 | — | — | US | disclosed |
| EP-1171414-A1 | COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000063153-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-10-26 | — | — | WO | disclosed |