Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7528425 | 0.86 | MAPT (1.00) | MAPTKDM4ERAB9AGAAL3MBTL1 | |
| SCHEMBL7052329 | 0.83 | MAPT (0.72) | MAPTKDM4ERAB9AGAAL3MBTL1 | |
| SCHEMBL7110619 | 0.82 | MAPT (0.74) | MAPTKDM4ERAB9AGAAL3MBTL1 | |
| SCHEMBL8569584 | 0.81 | MAPT (0.73) | MAPTKDM4EGAAL3MBTL1ALDH1A1 | |
| SCHEMBL8570351 | 0.81 | MAPT (0.73) | MAPTKDM4ERAB9AGAAL3MBTL1 | |
| SCHEMBL3841693 | 0.80 | MAPT (0.75) | MAPTKDM4ERAB9AGAAL3MBTL1 | |
| SCHEMBL7953536 | 0.79 | MAPT (0.69) | MAPTKDM4ERAB9AGAAL3MBTL1 | |
| SCHEMBL8065139 | 0.78 | MAPT (0.72) | MAPTKDM4ERAB9AGAAL3MBTL1 | |
| SCHEMBL8573524 | 0.78 | MAPT (0.71) | MAPTKDM4ERAB9AGAAL3MBTL1 | |
| SCHEMBL7612444 | 0.78 | MAPT (0.67) | MAPTKDM4ERAB9AGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7692020-B2 | Process for the preparation of pyridylcarboxylic amides and esters | BASF SE (DE) | 2010-04-06 | — | — | US | disclosed |
| US-7692020-B2 | Process for the preparation of pyridylcarboxylic amides and esters | BASF SE (DE) | 2010-04-06 | — | — | US | disclosed |
| US-20080249313-A1 | Process for the Preparation of Pyridylcarboxylic Amides and Esters | BASF SE (DE) | 2008-10-09 | — | — | US | disclosed |
| US-20080249313-A1 | Process for the Preparation of Pyridylcarboxylic Amides and Esters | BASF SE (DE) | 2008-10-09 | — | — | US | disclosed |
| WO-2007051759-A1 | PROCESS FOR THE PREPARATION OF PYRIDYLCARBOXYLIC AMIDES AND ESTERS | BASF SE (DE) | 2007-05-10 | — | — | WO | disclosed |
| EP-0899262-B1 | Process for the preparation of heteroarylcarboxylic amides and esters | BASF AG (DE) | 2005-04-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249313-A1 | Process for the Preparation of Pyridylcarboxylic Amides and Esters | ADH1C, ADH1A, CBR1 | MAPT 3875/4885KDM4E 1648/4885RAB9A 2818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.