⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10669809 | 0.76 | — | — | |
| SCHEMBL28476403 | 0.76 | — | — | |
| SCHEMBL10519878 | 0.76 | ARG1 (0.33) | — | |
| SCHEMBL6860632 | 0.76 | ARG1 (0.33) | — | |
| SCHEMBL221457 | 0.68 | — | — | |
| SCHEMBL7488055 | 0.67 | CYP4F2 (0.30) | — | |
| SCHEMBL1636613 | 0.65 | — | — | |
| SCHEMBL9212453 | 0.64 | — | — | |
| SCHEMBL7313574 | 0.63 | CYP4F2 (0.31) | — | |
| SCHEMBL7735878 | 0.63 | BTK (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050059606-A1 | Novel peptides as NS3-serine protease inhibitors of hepatitis C virus | DENDREON CORPORATION (US) | 2005-03-17 | — | — | US | disclosed |
| US-6800434-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION | 2004-10-05 | — | — | US | disclosed |
| EP-1301528-A2 | PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS | SCHERING CORPORATION (US) | 2003-04-16 | — | — | EP | disclosed |
| US-20030036501-A1 | Novel peptides as NS3-serine protease inhibitors of hepatitis C virus | DENDREON PHARMACEUTICALS LLC | 2003-02-20 | — | — | US | disclosed |
| WO-2002008256-A2 | PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS | SCHERING CORPORATION (US) | 2002-01-31 | — | — | WO | disclosed |