SCHEMBL6423318

SCHEMBL6423318

Cc1cc([Mg]Br)c(C)cc1[Mg]Br

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3005730 0.94 CYP3A4 (0.41) CYP3A4TSHRMAPK1
SCHEMBL636709 0.75 TDP1 (0.42) CYP3A4MAPK1
SCHEMBL30645502 0.75 TDP1 (0.42) CYP3A4MAPK1
SCHEMBL29435946 0.72 ACHE (0.35)
SCHEMBL362696 0.72 CYP3A4 (0.41) CYP3A4TSHR
SCHEMBL5426931 0.67 CRHR1 (0.35) CYP3A4
SCHEMBL959600 0.67
SCHEMBL29881812 0.67
SCHEMBL1022119 0.64 TRPA1 (0.42) CYP3A4TSHR
SCHEMBL29456798 0.64 TRPA1 (0.42) CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6885038-B2 Light-emitting polymers and polymer light-emitting diodes AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2005-04-26 US disclosed
US-20030088043-A1 Light-emitting polymers and polymer light-emitting diodes AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2003-05-08 US disclosed