SCHEMBL642345

SCHEMBL642345

COC(=O)c1cccc(Cl)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.59
NPC1 O15118 5/20 0.59
MAPT P10636 3/20 0.59
POLB P06746 2/20 0.57
GFER P55789 1/20 0.57
TSHR P16473 1/20 0.57
PARP1 P09874 1/20 0.57
ATM Q13315 1/20 0.56
LOXL2 Q9Y4K0 1/20 0.56
CYP4F2 P78329 1/20 0.54
CYP4A11 Q02928 1/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
CYP1A2 P05177 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
HPGD P15428 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29406761 1.00 RAB9A (0.59) RAB9ANPC1MAPTPOLBGFER
Carbon Monoxide SCHEMBL10625114 0.94 RAB9A (0.55) RAB9ANPC1MAPTPOLBGFER
SCHEMBL1681182 0.94 RAB9A (0.55) RAB9ANPC1MAPTPOLBGFER
Methylene Chloride SCHEMBL29256423 0.94 LOXL2 (0.56) RAB9ANPC1MAPTPOLBGFER
SCHEMBL7467547 0.93 POLB (0.55) RAB9ANPC1MAPTPOLBGFER
SCHEMBL27404769 0.93 POLB (0.55) RAB9ANPC1MAPTPOLBGFER
SCHEMBL7827008 0.89 PLAU (0.59) RAB9ANPC1MAPTTSHRATM
SCHEMBL5928176 0.86 RAB9A (0.62) RAB9ANPC1MAPTPOLBTSHR
SCHEMBL1814183 0.86 RAB9A (0.73) RAB9ANPC1MAPTATMMEN1
SCHEMBL34953 0.85 TSHR (0.70) RAB9ANPC1MAPTPOLBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 361 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118084672-A Method for preparing 5-chloro-2-nitrobenzoic acid methyl ester by adopting microchannel reactor 常州大学 2024-05-28 CN claimed
US-10224485-B2 Process for preparing a crystalline organic semiconductor material BASF SE (DE) 2019-03-05 US claimed
US-20170012208-A1 ORGANIC SEMICONDUCTOR FORMULATIONS USINVEST LLC 2017-01-12 US claimed
US-20150322094-A1 USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2015-11-12 US claimed
EP-2892343-A1 USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS Bayer CropScience AG (DE) 2015-07-15 EP claimed
WO-2014037349-A1 USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2014-03-13 WO claimed
US-8569195-B2 Internal and external donor compounds for olefin polymerization catalysts II BASF CORPORATION (US) 2013-10-29 US claimed
EP-2539375-A2 INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS II BASF Corporation (US) 2013-01-02 EP claimed
WO-2011106480-A2 INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS II BASF CORPORATION (US) 2011-09-01 WO claimed
US-20110207901-A1 INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS II BASF CATALYSTS LLC (US) 2011-08-25 US claimed
US-4939309-A REACTING ARYL HALIDE WITH NICKEL-ORGANOPHOSPHINE-ORGANOMETAL-LIC-BIDENTATE LIGAND CATALYST EASTMAN KODAK COMPANY (US) 1990-07-03 US claimed
US-4314070-A REACTING ALKALI PHENATE WITH ALKYL META-HALOBENZOATE, COPPER SULFATE CATALYST RHONE-POULENC INC. (US) 1982-02-02 US claimed
EP-0021868-B1 PROCESS FOR THE PREPARATION OF DIARYL ETHERS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1981-12-23 EP claimed
US-4288386-A Ullmann reaction for the synthesis of diaryl ethers RHONE-POULENC INDUSTRIES (FR) 1981-09-08 US claimed
JP-61161242-A None JP disclosed
EP-3684374-B1 4'-FLUORO-2'-METHYL SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF HCV RNA REPLICATION RIBOSCIENCE LLC (US) 2025-07-30 EP disclosed
EP-3634403-B1 PHENYL-HETEROCYCLE-PHENYL DERIVATIVES FOR USE IN THE TREATMENT OR PREVENTION OF MELANOMA MAX PLANCK GESELLSCHAFT (DE) 2025-06-25 EP disclosed
US-4267294-A COMPOSED OF A TITANIUM HALIDE ON A MAGNESIUM HALIDE SUPPORT WITH A TRIALKYLALUMINUM-DIALKYLALUMINUM HYDRIDE-AROMATIC ACID ALKYL ESTER ACTIVATOR HERCULES INCORPORATED (US) 1981-05-12 US disclosed
US-4250287-A TITANIUM HALIDE, MAGNESIUM HALIDE, TRIALKYLALUMINUM ON SUPPORT WITH HALOSILANE ACTIVATOR HERCULES INCORPORATED (US) 1981-02-10 US disclosed
US-4211670-A ELECTRON DONOR COMPOUNDS HERCULES INCORPORATED (US) 1980-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150322094-A1 USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS CAT, HSF1, HPD RAB9A 3029/4885NPC1 3919/4885MAPT 3867/4885
US-10224485-B2 Process for preparing a crystalline organic semiconductor material STOM, SPOP, TTR RAB9A 1863/4885NPC1 917/4885MAPT 150/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.