Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6426555 | 0.98 | PTGS2 (0.38) | PPARGPTGS2ABCB1PTGS1MEN1 | |
| SCHEMBL6422766 | 0.90 | MEN1 (0.35) | PPARGPTGS2ABCB1MEN1KMT2A | |
| SCHEMBL6423710 | 0.90 | PTGS2 (0.47) | PPARGPTGS2ABCB1PTGS1MEN1 | |
| SCHEMBL6423643 | 0.89 | MGLL (0.39) | PPARGPTGS2ABCB1PTGS1 | |
| SCHEMBL6422650 | 0.89 | MEN1 (0.37) | PPARGPTGS2ABCB1MEN1KMT2A | |
| SCHEMBL5553716 | 0.88 | AKR1C3 (0.39) | PTGS2PTGS1RAB9AAKR1C3AKR1C2 | |
| SCHEMBL6423862 | 0.88 | PTGS2 (0.43) | PPARGPTGS2ABCB1PTGS1MEN1 | |
| SCHEMBL6424495 | 0.88 | PTGS2 (0.37) | PTGS2ABCB1PTGS1MAPTAKR1C3 | |
| SCHEMBL6425925 | 0.88 | PTGS2 (0.47) | PPARGPTGS2ABCB1PTGS1MEN1 | |
| SCHEMBL5559188 | 0.87 | PTGS2 (0.39) | PPARGPTGS2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | IRONWOOD PHARMACEUTICALS, INC. | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | FAAH2, FAAH, PTGES2 | PPARG 1908/4885PTGS2 4/4885ABCB1 2922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.