Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK7 | Q13164 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6427087 | 0.98 | NR1H4 (0.36) | MAPK7NR1H4KMT2AALDH1A1RAB9A | |
| SCHEMBL6425909 | 0.91 | PTGS2 (0.39) | MAPK7NR1H4ALDH1A1L3MBTL1LMNA | |
| SCHEMBL6424446 | 0.89 | PTGS1 (0.42) | MAPK7KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL6426648 | 0.89 | PTGS2 (0.39) | MAPK7NR1H4ALDH1A1LMNA | |
| SCHEMBL6424118 | 0.88 | KMT2A (0.33) | KMT2AALDH1A1LMNAHTTMAPT | |
| SCHEMBL6424805 | 0.88 | PTGS1 (0.42) | MAPK7KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL5558666 | 0.86 | KMT2A (0.33) | KMT2AALDH1A1RAB9ANPC1SRD5A2 | |
| SCHEMBL6423785 | 0.85 | AKR1C3 (0.41) | MAPK7NR1H4KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6424402 | 0.85 | LMNA (0.37) | KMT2ARAB9AHRH3LMNAMAPK1 | |
| SCHEMBL6425557 | 0.84 | LMNA (0.35) | KMT2ARAB9AHRH3LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | IRONWOOD PHARMACEUTICALS, INC. | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | FAAH2, FAAH, PTGES2 | MAPK7 2506/4885NR1H4 1725/4885KMT2A 1519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.