Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | BUB1 | O43683 | 1/20 | 0.33 |
| ▸ | WRN | Q14191 | 1/20 | 0.32 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6421909 | 0.85 | MAPT (0.33) | ALPLMAPTBUB1WRN | |
| SCHEMBL7123071 | 0.84 | ALPL (0.36) | ALPLPTGDR2PTGDRMAPTBUB1 | |
| SCHEMBL6422907 | 0.84 | ALPL (0.39) | ALPLMAPTBUB1WRNHSP90AA1 | |
| SCHEMBL6421617 | 0.83 | CETP (0.42) | PTGDR2PTGDRCNR1CNR2SSTR5 | |
| SCHEMBL8129664 | 0.80 | MAPT (0.45) | ALPLMAPTALDH1A1TP53NPSR1 | |
| SCHEMBL6424437 | 0.77 | CETP (0.36) | PTGDR2PTGDRCNR2SSTR5ALOX5AP | |
| SCHEMBL6423040 | 0.77 | ALPL (0.34) | ALPLMAPTBUB1WRNOPRM1 | |
| SCHEMBL7127715 | 0.72 | ALPL (0.34) | ALPLMAPTBUB1SSTR5OPRM1 | |
| SCHEMBL7122832 | 0.71 | ALPL (0.40) | ALPLMAPTBUB1WRNHSP90AA1 | |
| SCHEMBL6376468 | 0.69 | GCGR (0.38) | ALPLMAPTBUB1WRNOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017659-B1 | SUBSTITUTED TETRAHYDRONAPHTHALINE AND ANALOGOUS COMPOUNDS | BAYER HEALTHCARE AG (DE) | 2005-04-27 | — | — | EP | disclosed |
| EP-1017659-A1 | SUBSTITUTED TETRAHYDRONAPHTHALINE AND ANALOGOUS COMPOUNDS | BAYER AG (DE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999014174-A1 | SUBSTITUTED TETRAHYDRONAPHTHALINE AND ANALOGOUS COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-25 | — | — | WO | disclosed |