Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 6/20 | 0.35 |
| ▸ | TACR2 | P21452 | 4/20 | 0.35 |
| ▸ | TACR1 | P25103 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 3/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6424012 | 0.98 | PDE2A (0.35) | PDE2ATACR3TACR2TACR1KCNH2 | |
| SCHEMBL6424443 | 0.94 | HSD11B1 (0.37) | CYP3A4CYP2D6HSD11B1 | |
| SCHEMBL6425459 | 0.93 | TSHR (0.38) | KCNH2NR1H4CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6427479 | 0.93 | MEN1 (0.36) | PDE2ATACR3TACR2KCNH2MGLL | |
| SCHEMBL6423103 | 0.91 | AKR1C3 (0.39) | KCNH2MGLLNR1H4CYP3A4CYP2D6 | |
| SCHEMBL6427372 | 0.91 | MEN1 (0.36) | PDE2AKCNH2MGLLNR1H4CYP3A4 | |
| SCHEMBL6426945 | 0.90 | PDE2A (0.35) | PDE2ATACR3TACR2TACR1KCNH2 | |
| SCHEMBL6423869 | 0.89 | AKR1C3 (0.39) | KCNH2NR1H4CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6423582 | 0.88 | PDE2A (0.35) | PDE2ATACR3TACR2TACR1KCNH2 | |
| SCHEMBL6426725 | 0.88 | ALDH1A1 (0.37) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | IRONWOOD PHARMACEUTICALS, INC. | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | FAAH2, FAAH, PTGES2 | PDE2A 846/4885TACR3 3985/4885TACR2 2967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.