Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6426827 | 1.00 | ALDH1A1 (0.39) | ALDH1A1HPGDMEN1KMT2APOLB | |
| SCHEMBL6425602 | 0.97 | ALDH1A1 (0.38) | ALDH1A1HPGDMEN1KMT2APOLB | |
| SCHEMBL6423399 | 0.95 | MEN1 (0.36) | ALDH1A1HPGDMEN1KMT2APOLB | |
| SCHEMBL6425499 | 0.95 | MEN1 (0.36) | ALDH1A1HPGDMEN1KMT2APOLB | |
| SCHEMBL6425670 | 0.92 | LMNA (0.36) | ALDH1A1ELANECTRCLMNA | |
| SCHEMBL6423335 | 0.92 | LMNA (0.36) | ALDH1A1ELANECTRCLMNA | |
| SCHEMBL6423695 | 0.91 | MEN1 (0.39) | ALDH1A1HPGDMEN1KMT2APOLB | |
| SCHEMBL6427423 | 0.91 | MEN1 (0.39) | ALDH1A1HPGDMEN1KMT2APOLB | |
| SCHEMBL6428421 | 0.90 | AKR1C3 (0.33) | MEN1KMT2AELANECTRC | |
| SCHEMBL6424844 | 0.90 | AKR1C3 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | IRONWOOD PHARMACEUTICALS, INC. | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | FAAH2, FAAH, PTGES2 | ALDH1A1 630/4885HPGD 15/4885MEN1 3824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.