SCHEMBL6426028

SCHEMBL6426028

COP(=O)(OC)OCC#N

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7616328 0.95 TSHR (0.32) TSHRACHE
SCHEMBL6645670 0.84 TSHR (0.38) TSHRACHE
SCHEMBL8306942 0.78
SCHEMBL561742 0.78 TSHR (0.62) TSHRACHE
SCHEMBL11907935 0.76 CYP3A4 (0.34) TSHR
SCHEMBL6422945 0.76
SCHEMBL6426351 0.75 ACHE (0.41) TSHRACHE
SCHEMBL3902813 0.75 CTSA (0.41) ACHE
SCHEMBL29208316 0.75 CYP3A4 (0.48) TSHRACHE
SCHEMBL14118484 0.74 ACHE (0.35) TSHRACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118812389-A Synthesis method of 2,3,5, 6-tetrafluorobenzyl (1R, 3R) -3- ((Z) -2-cyanovinyl) -2, 2-dimethylcyclopropane carboxylic ester and isomer thereof 江苏扬农化工股份有限公司 2024-10-22 CN claimed
CN-117720575-A Hole transport material and preparation method and application thereof 深圳普太科技有限公司 2024-03-19 CN claimed
US-6919141-B2 Phosphate additives for nonaqueous electrolyte rechargeable electrochemical cells WILSON GREATBATCH TECHNOLOGIES, INC. (US) 2005-07-19 US claimed
US-20030113635-A1 Phosphate additives for nonaqueous electrolyte rechargeable electrochemical cells GREATBATCH, INC. 2003-06-19 US claimed
US-6511772-B2 Electrochemical cell having an electrode with a phosphate additive in the electrode active mixture WILSON GREATBATCH LTD. 2003-01-28 US claimed
US-20020094479-A1 Electrochemical cell having an electrode with a phosphate additive in the electrode active mixture GREATBATCH, INC. 2002-07-18 US claimed
EP-1213782-A2 Phosphate additives for nonaqueous electrolyte rechargeable electrochemical cells WILSON GREATBATCH LTD. (US) 2002-06-12 EP claimed
CN-117720575-B Hole transport material and preparation method and application thereof 深圳普太科技有限公司 2024-11-12 CN disclosed
CN-118812389-A Synthesis method of 2,3,5, 6-tetrafluorobenzyl (1R, 3R) -3- ((Z) -2-cyanovinyl) -2, 2-dimethylcyclopropane carboxylic ester and isomer thereof 江苏扬农化工股份有限公司 2024-10-22 CN disclosed
CN-116375604-B Double-bond cyano-containing pyrethroid compound, and synthetic method and application thereof 江苏扬农化工股份有限公司 2024-10-22 CN disclosed
CN-118724948-A Dual-function self-assembled hole transport material and preparation method and application thereof 深圳普太科技有限公司 2024-10-01 CN disclosed
CN-117720575-A Hole transport material and preparation method and application thereof 深圳普太科技有限公司 2024-03-19 CN disclosed
WO-2023160316-A1 PYRETHROID COMPOUND CONTAINING DOUBLE BONDS AND CYANO GROUPS, SYNTHESIS METHOD THEREFOR, AND APPLICATION THEREOF 江苏扬农化工股份有限公司 2023-08-31 WO disclosed
CN-116375604-A Double-bond cyano-containing pyrethroid compound, and synthetic method and application thereof 江苏扬农化工股份有限公司 2023-07-04 CN disclosed
US-10759812-B2 Thienopyrimidine derivative and use thereof in medicine SUNSHINE LAKE PHARMA CO., LTD. (CN) 2020-09-01 US disclosed
US-20190352311-A1 THIENOPYRIMIDINE DERIVATIVE AND USE THEREOF IN MEDICINE SUNSHINE LAKE PHARMA CO., LTD. (CN) 2019-11-21 US disclosed
US-20130224604-A1 ELECTROLYTE FOR SECONDARY LITHIUM BATTERY AND SECONDARY LITHIUM BATTERY INCLUDING SAME SAMSUNG SDI CO., LTD. (KR) 2013-08-29 US disclosed
US-20130224604-A1 ELECTROLYTE FOR SECONDARY LITHIUM BATTERY AND SECONDARY LITHIUM BATTERY INCLUDING SAME SAMSUNG SDI CO., LTD. (KR) 2013-08-29 US disclosed
US-6511772-B2 Electrochemical cell having an electrode with a phosphate additive in the electrode active mixture WILSON GREATBATCH LTD. 2003-01-28 US disclosed
US-20020094479-A1 Electrochemical cell having an electrode with a phosphate additive in the electrode active mixture GREATBATCH, INC. 2002-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190352311-A1 THIENOPYRIMIDINE DERIVATIVE AND USE THEREOF IN MEDICINE ACACA, ACACB, PC TSHR 4068/4885ACHE 1449/4885
US-10759812-B2 Thienopyrimidine derivative and use thereof in medicine ACACA, ACACB, PC TSHR 4068/4885ACHE 1449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.