⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14118484 | 0.87 | ACHE (0.35) | — | |
| SCHEMBL6426028 | 0.78 | TSHR (0.32) | — | |
| SCHEMBL7616328 | 0.78 | TSHR (0.32) | — | |
| SCHEMBL11237347 | 0.77 | — | — | |
| SCHEMBL11358584 | 0.76 | — | — | |
| SCHEMBL6422945 | 0.74 | — | — | |
| SCHEMBL14118485 | 0.73 | — | — | |
| SCHEMBL17888972 | 0.71 | PKM (0.41) | — | |
| SCHEMBL6645670 | 0.71 | TSHR (0.38) | — | |
| Dimethyl Methylphosphonate SCHEMBL27854417 | 0.71 | CA2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4520101-A | FERMENTATION WITH ADDITION OF PHOSPHORUS COMPOUNDS | BRISTOL-MYERS COMPANY (US) | 1985-05-28 | — | — | US | claimed |
| EP-0469833-B1 | N-Benzyl-Indoles, processes for their preparation and pharmaceutical compositions containing them | LILLY CO ELI (GB) | 1999-09-08 | — | — | EP | disclosed |
| US-5622969-A | ADMINISTERING TO HUMAN OR ANIMAL SUFFERING FROM ALLERGIC REACTION OF PULMONARY SYSTEM AND OTHER INFLAMMATORY DISORDERS | ELI LILLY AND COMPANY (US) | 1997-04-22 | — | — | US | disclosed |
| US-5569764-A | USEFUL FOR TREATING ALLERGIC REACTIONS OF PULMONARY SYSTEM, ALLERGIC SKIN DISEASES, RHEUMATIC FEVER, CYSTIC FIBROSIS, AND VASCULAR DISEASES | ELI LILLY AND COMPANY (US) | 1996-10-29 | — | — | US | disclosed |
| US-5486612-A | FOR TREATING DISEASES WHICH LEUKOTRIENES MEDIATE | ELI LILLY AND COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| EP-0658554-A1 | N-benzyl dihydroindole LTD4 antagonists | ELI LILLY AND COMPANY (US) | 1995-06-21 | — | — | EP | disclosed |
| US-5374641-A | Thromboxane synthetase inhibitors, prostaglandin H2 antagonist , anticoagulants and antiallergens | TERUMO KABUSHIKI KAISHA (JP) | 1994-12-20 | — | — | US | disclosed |
| US-5281593-A | Pharmaceuticals | LILLY INDUSTRIES LIMITED (GB) | 1994-01-25 | — | — | US | disclosed |
| EP-0501876-A1 | N-(3-pyridylalkyl)sulfonamide derivative and pharmaceutical preparation containing thereof | TERUMO KABUSHIKI KAISHA (JP) | 1992-09-02 | — | — | EP | disclosed |
| EP-0469833-A1 | N-Benzyl-Indoles, processes for their preparation and pharmaceutical compositions containing them | LILLY INDUSTRIES LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| US-5025002-A | Broad spectrum biocide, industrial process systems | BROMINE COMPOUNDS LTD. (IL) | 1991-06-18 | — | — | US | disclosed |
| US-4520101-A | FERMENTATION WITH ADDITION OF PHOSPHORUS COMPOUNDS | BRISTOL-MYERS COMPANY (US) | 1985-05-28 | — | — | US | disclosed |