Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 5/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6424919 | 0.98 | MEN1 (0.37) | MEN1KMT2AMGLLFAAHHSD11B1 | |
| SCHEMBL6425963 | 0.92 | PDE2A (0.35) | MGLLFAAHKCNH2PDE2AAKR1C3 | |
| SCHEMBL6423179 | 0.91 | AKR1C3 (0.41) | MEN1KMT2AMGLLCYP2D6CYP2C9 | |
| SCHEMBL6426792 | 0.91 | AKR1C3 (0.37) | MEN1KMT2AMGLLHSD11B1AKR1C3 | |
| SCHEMBL6424892 | 0.91 | LMNA (0.34) | MEN1KMT2AMGLLFAAHHSD11B1 | |
| SCHEMBL6423781 | 0.90 | PDE2A (0.35) | MGLLFAAHKCNH2PDE2ANR1H4 | |
| SCHEMBL6426808 | 0.90 | HSD11B1 (0.37) | MGLLFAAHHSD11B1PGRAKR1C3 | |
| SCHEMBL6425689 | 0.90 | SRC (0.39) | KMT2AMGLLFAAHHSD11B1AKR1C3 | |
| SCHEMBL6425613 | 0.90 | AKR1C3 (0.41) | MGLLKCNH2NR1H4CYP3A4CYP2D6 | |
| SCHEMBL6423904 | 0.89 | AKR1C3 (0.37) | MEN1KMT2AMGLLHSD11B1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | IRONWOOD PHARMACEUTICALS, INC. | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | FAAH2, FAAH, PTGES2 | MEN1 3824/4885KMT2A 1519/4885MGLL 108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.