Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.44 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PDE1A | P54750 | 1/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6430925 | 0.85 | PRKAG1 (0.46) | KMT2ANR1H2NR1H3PRKAG1PRKAB1 | |
| SCHEMBL6427927 | 0.83 | MAPT (0.52) | KMT2ANR1H2NR1H3MAPTKDM4E | |
| SCHEMBL6428843 | 0.79 | NR1H2 (0.52) | ADRA1DKMT2ANR1H2NR1H3MAPT | |
| SCHEMBL6426743 | 0.77 | CMA1 (0.57) | ADRA1DKMT2ANR1H2NR1H3MAPT | |
| SCHEMBL6428883 | 0.76 | NR1H2 (0.48) | KMT2ANR1H2NR1H3MAPTKDM4E | |
| SCHEMBL6427708 | 0.76 | NR1H2 (0.50) | KMT2ANR1H2NR1H3MAPTKDM4E | |
| SCHEMBL6426484 | 0.76 | APAF1 (0.52) | KMT2ANR1H2NR1H3MAPTPOLB | |
| SCHEMBL6427000 | 0.75 | NR1H2 (0.60) | KMT2ANR1H2NR1H3MAPTKDM4E | |
| SCHEMBL6426845 | 0.72 | MAPT (0.50) | KMT2ANR1H2NR1H3MAPTMAPK1 | |
| SCHEMBL6427394 | 0.70 | NR1H2 (0.51) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005024755-A2 | MEDICAMENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS OR DIABETES | DECIPHERA PHARMACEUTICALS, LLC. (US) | 2005-03-17 | — | — | WO | disclosed |